Literature DB >> 19412695

[Current diagnosis of acute pharyngitis].

Berthold Reichardt1, Otto Pichlhöfer, Sonja Zehetmayer, Manfred Maier.   

Abstract

BACKGROUND: Throat infections with Group A Streptococci have a high incidence and are, therefore, a considerable health problem. It is, therefore, desirable to distinguish this bacterial infections from viral infections of the upper respiratory tract. We report about the application of an immunologic rapid antigen detection test for Group A Streptococci and its medical and economic implications.
METHODS: In a cross-sectional cohort study, 30 family physicians documented the application of the test in 519 patients. Follow-up costs were compared with 109 family physicians who did not have access to the test.
RESULTS: 40.27% of tests performed were positive for Streptococci. 99% of those patients received antibiotic treatment - predominantly with Penicillin. From those patients who had shown a negative test result, only 18.4% received antibiotic treatment. Both patients and physicians welcomed the availability of the test. We did not find any significant difference regarding the economic effect of the test.
CONCLUSIONS: The employment of a rapid antigen detection test for Group A Streptococci in patients with acute pharyngitis increases therapeutic certitude and guideline-conform prescription of antibiotics among family physicians. We, therefore, assume that potential side effects of unnecessary antibiotic treatments could be minimized.

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Year:  2009        PMID: 19412695     DOI: 10.1007/s10354-009-0672-x

Source DB:  PubMed          Journal:  Wien Med Wochenschr        ISSN: 0043-5341


  17 in total

Review 1.  Antimicrobial resistance: current status and future direction.

Authors:  Michael A Saubolle
Journal:  Am J Rhinol       Date:  2006 Nov-Dec

2.  [Difficulty in swallowing].

Authors:  H Wächtler; E Baum
Journal:  MMW Fortschr Med       Date:  2007-10-25

3.  Group A streptococcal infections.

Authors:  Preeti Jaggi; Stanford T Shulman
Journal:  Pediatr Rev       Date:  2006-03

4.  Antibiotic prescribing for self limiting respiratory tract infections in primary care: summary of NICE guidance.

Authors:  Toni Tan; Paul Little; Tim Stokes
Journal:  BMJ       Date:  2008-07-23

Review 5.  Bacterial resistance: a sensitive issue complexity of the challenge and containment strategy in Europe.

Authors:  W T M Jansen; J T van der Bruggen; J Verhoef; A C Fluit
Journal:  Drug Resist Updat       Date:  2006-06-27       Impact factor: 18.500

Review 6.  The global burden of group A streptococcal diseases.

Authors:  Jonathan R Carapetis; Andrew C Steer; E Kim Mulholland; Martin Weber
Journal:  Lancet Infect Dis       Date:  2005-11       Impact factor: 25.071

Review 7.  Differences among international pharyngitis guidelines: not just academic.

Authors:  Jan Matthys; Marc De Meyere; Mieke L van Driel; An De Sutter
Journal:  Ann Fam Med       Date:  2007 Sep-Oct       Impact factor: 5.166

Review 8.  A half-century of streptococcal research: then & now.

Authors:  Richard M Krause
Journal:  Indian J Med Res       Date:  2002-06       Impact factor: 2.375

9.  Protective effect of antibiotics against serious complications of common respiratory tract infections: retrospective cohort study with the UK General Practice Research Database.

Authors:  I Petersen; A M Johnson; A Islam; G Duckworth; D M Livermore; A C Hayward
Journal:  BMJ       Date:  2007-10-18

10.  Optimal management of adults with pharyngitis--a multi-criteria decision analysis.

Authors:  Sonal Singh; James G Dolan; Robert M Centor
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  4 in total

1.  [Questions and developments in the general medicine specialty].

Authors:  Manfred Maier
Journal:  Wien Med Wochenschr       Date:  2009

2.  Evaluation of the implementation of a rapid streptococcal antigen test in a routine primary health care setting: from recommendations to practice.

Authors:  Kathryn Hoffmann; Berthold Reichardt; Sonja Zehetmayer; Manfred Maier
Journal:  Wien Klin Wochenschr       Date:  2012-08-10       Impact factor: 1.704

Review 3.  Rapid antigen detection test for group A streptococcus in children with pharyngitis.

Authors:  Jérémie F Cohen; Nathalie Bertille; Robert Cohen; Martin Chalumeau
Journal:  Cochrane Database Syst Rev       Date:  2016-07-04

4.  Efficacy and safety of rapid tests to guide antibiotic prescriptions for sore throat.

Authors:  Jérémie F Cohen; Jean-Yves Pauchard; Nils Hjelm; Robert Cohen; Martin Chalumeau
Journal:  Cochrane Database Syst Rev       Date:  2020-06-04
  4 in total

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