Literature DB >> 19411855

Antioxidant defense and aging in C. elegans: is the oxidative damage theory of aging wrong?

David Gems1, Ryan Doonan.   

Abstract

The oxidative damage theory of aging once seemed almost proven. Yet recently the buzzards have been assembling in the blue skies above it. New challenges to the theory from work using nematode worms seem set to bring them down to peck at its bones. But is the theory really dead, or does it just need to be modified?

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Year:  2009        PMID: 19411855     DOI: 10.4161/cc.8.11.8595

Source DB:  PubMed          Journal:  Cell Cycle        ISSN: 1551-4005            Impact factor:   4.534


  110 in total

1.  Integration of immunity with physical and cognitive function in definitions of successful aging.

Authors:  Patricia Griffin; Joshua J Michel; Kristy Huysman; Alison J Logar; Abbe N Vallejo
Journal:  Aging Dis       Date:  2012-02-27       Impact factor: 6.745

Review 2.  Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences.

Authors:  Nicole Exner; Anne Kathrin Lutz; Christian Haass; Konstanze F Winklhofer
Journal:  EMBO J       Date:  2012-06-26       Impact factor: 11.598

Review 3.  Progeria syndromes and ageing: what is the connection?

Authors:  Christopher R Burtner; Brian K Kennedy
Journal:  Nat Rev Mol Cell Biol       Date:  2010-08       Impact factor: 94.444

Review 4.  The genetics of ageing.

Authors:  Cynthia J Kenyon
Journal:  Nature       Date:  2010-03-25       Impact factor: 49.962

5.  Antioxidants can extend lifespan of Brachionus manjavacas (Rotifera), but only in a few combinations.

Authors:  Terry W Snell; Allison M Fields; Rachel K Johnston
Journal:  Biogerontology       Date:  2012-01-24       Impact factor: 4.277

6.  Nrf2, a guardian of healthspan and gatekeeper of species longevity.

Authors:  Kaitlyn N Lewis; James Mele; John D Hayes; Rochelle Buffenstein
Journal:  Integr Comp Biol       Date:  2010-05-06       Impact factor: 3.326

Review 7.  Relationship of electrophilic stress to aging.

Authors:  Piotr Zimniak
Journal:  Free Radic Biol Med       Date:  2011-06-12       Impact factor: 7.376

Review 8.  Oxidation as an important factor of protein damage: Implications for Maillard reaction.

Authors:  L Trnkova; J Drsata; I Bousova
Journal:  J Biosci       Date:  2015-06       Impact factor: 1.826

9.  Extension of Health Span and Life Span in Drosophila by S107 Requires the calstabin Homologue FK506-BP2.

Authors:  Tabita Kreko-Pierce; Jorge Azpurua; Rebekah E Mahoney; Benjamin A Eaton
Journal:  J Biol Chem       Date:  2016-11-01       Impact factor: 5.157

Review 10.  Role of reactive oxygen species-mediated signaling in aging.

Authors:  Vyacheslav M Labunskyy; Vadim N Gladyshev
Journal:  Antioxid Redox Signal       Date:  2012-09-20       Impact factor: 8.401

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