Literature DB >> 19411438

Spontaneous pneumomediastinum: analysis of 62 consecutive adult patients.

Vivek N Iyer1, Avni Y Joshi, Jay H Ryu.   

Abstract

OBJECTIVE: To clarify the clinical presentation and course of patients with spontaneous pneumomediastinum (SP) and to determine the usefulness of diagnostic testing in these patients. PATIENTS AND METHODS: We conducted a retrospective review of 62 consecutive adult patients (age >or=18 years) diagnosed as having SP during an 11-year period from July 1, 1997, to June 30, 2008. The study cohort included 41 men and 21 women (median age, 30 years; interquartile range, 20-69 years).
RESULTS: Among the 62 study patients, the most common presenting symptoms were chest pain (39 patients [63%]), cough (28 [45%]), and dyspnea (27 [44%]). Preexisting lung diseases were identified in 27 patients (44%) and included interstitial lung disease, asthma, lung malignancies, bronchiolitis obliterans syndrome, chronic obstructive pulmonary disease, bronchiectasis, and cystic lung lesions. The initial diagnosis of SP was achieved by chest radiography in 52 patients (84%); the remaining cases were diagnosed by computed tomography. Forty-seven patients (76%) were hospitalized for a median duration of 2.5 days. Additional diagnostic procedures were performed in 27 patients (44%) and included contrast esophagography, bronchoscopy, and esophagogastroduodenoscopy; however, they did not yield a pathologic cause in any patient. Pneumothorax was identified in 20 patients (32%), but less than one-third of these patients underwent chest tube thoracostomy. No episodes of mediastinitis or sepsis occurred. Recurrence of SP was seen in 1 patient, and thoracoscopic surgery was performed in 1 patient for persistent air leak (pneumothorax).
CONCLUSION: Spontaneous pneumomediastinum was associated with a relatively benign clinical course; however, pneumothorax was seen in 32% of cases. Diagnostic testing to determine a pathologic cause yielded little clinically relevant information in these patients.

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Year:  2009        PMID: 19411438      PMCID: PMC2676124          DOI: 10.1016/S0025-6196(11)60560-0

Source DB:  PubMed          Journal:  Mayo Clin Proc        ISSN: 0025-6196            Impact factor:   7.616


  25 in total

1.  Spontaneous pneumomediastinum.

Authors:  A Ba-Ssalamah; W Schima; W Umek; C J Herold
Journal:  Eur Radiol       Date:  1999       Impact factor: 5.315

2.  Pneumomediastinum and pneumopericardium due to malignant subcarinal lymphadenopathy: CT demonstration.

Authors:  K Oberholzer; H U Kauczor; B Fischer; M Thelen
Journal:  Eur Radiol       Date:  1997       Impact factor: 5.315

3.  Pneumomediastinum and cervical emphysema from the inhalation of "free based" cocaine: report of three cases.

Authors:  D J Aroesty; R B Stanley; D M Crockett
Journal:  Otolaryngol Head Neck Surg       Date:  1986-03       Impact factor: 3.497

4.  Spontaneous pneumomediastinum long-term follow-up.

Authors:  Jorge Freixinet; Francisca García; Pedro M Rodríguez; Noberto B Santana; César O Quintero; Mohammed Hussein
Journal:  Respir Med       Date:  2005-04-01       Impact factor: 3.415

5.  Pneumomediastinum resulting from performing Valsalva maneuvers during marihuana smoking.

Authors:  W E Miller; R E Spiekerman; N G Hepper
Journal:  Chest       Date:  1972-08       Impact factor: 9.410

6.  Spontaneous pneumomediastinum in a patient with diabetic ketoacidosis: a potentially hidden complication.

Authors:  L S Weathers; W G Brooks; T J DeClue
Journal:  South Med J       Date:  1995-04       Impact factor: 0.954

7.  Recurrent pneumomediastinum in diabetic ketoacidosis.

Authors:  V J Nessan
Journal:  Postgrad Med       Date:  1974-06       Impact factor: 3.840

8.  Pneumomediastinum as a complication of "crack" smoking.

Authors:  S L Brody; G V Anderson; J B Gutman
Journal:  Am J Emerg Med       Date:  1988-05       Impact factor: 2.469

9.  Spontaneous pneumomediastinum. A report of 25 cases.

Authors:  I Abolnik; I S Lossos; R Breuer
Journal:  Chest       Date:  1991-07       Impact factor: 9.410

10.  Spontaneous pneumomediastinum: clinical and natural history.

Authors:  E A Panacek; A J Singer; B W Sherman; A Prescott; W F Rutherford
Journal:  Ann Emerg Med       Date:  1992-10       Impact factor: 5.721

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  35 in total

1.  Spontaneous pneumomediastinum associated with sex.

Authors:  Sam Flatman; Edwin Morrison; Maqsood Elahi
Journal:  J Radiol Case Rep       Date:  2010-04-01

2.  Spontaneous pneumomediastinum due to achalasia: an unusual but benign cause.

Authors:  Ramin Javan; Richard Duszak; Keith Tonkin
Journal:  J Radiol Case Rep       Date:  2010-11-01

3.  Spontaneous pneumomediastinum.

Authors:  Ankush Gupta; Imran Rizvi; Vijay Kumar Srivastava; Jyotindu Debnath; B N Kapur; V N Khanna; Atiya Aziz
Journal:  Med J Armed Forces India       Date:  2013-06-06

4.  Clinical experience of spontaneous pneumomediastinum: diagnosis and treatment.

Authors:  Kyung Soo Kim; Hyun Woo Jeon; Youngkyu Moon; Young Du Kim; Myeong Im Ahn; Jae Kil Park; Keon Hyun Jo
Journal:  J Thorac Dis       Date:  2015-10       Impact factor: 2.895

5.  Pneumomediastinum After Difficult Vaginal Delivery.

Authors:  Ahmet Sızlanan; Onur Akçay
Journal:  Turk Thorac J       Date:  2016-04-01

6.  Swollen neck and crepitus after bouts of cough.

Authors:  I Mohamad; B D Susibalan; Nfh Nik Hassan
Journal:  Malays Fam Physician       Date:  2013-12-31

7.  Spontaneous pneumomediastinum: two contrasting cases that highlight key aspects of management.

Authors:  Matthew David Kelham; Allan Zhifa Nghiem; April Lauren Goundry
Journal:  BMJ Case Rep       Date:  2014-10-31

Review 8.  Pneumomediastinum.

Authors:  Vasileios K Kouritas; Konstantinos Papagiannopoulos; George Lazaridis; Sofia Baka; Ioannis Mpoukovinas; Vasilis Karavasilis; Sofia Lampaki; Ioannis Kioumis; Georgia Pitsiou; Antonis Papaiwannou; Anastasia Karavergou; Maria Kipourou; Martha Lada; John Organtzis; Nikolaos Katsikogiannis; Kosmas Tsakiridis; Konstantinos Zarogoulidis; Paul Zarogoulidis
Journal:  J Thorac Dis       Date:  2015-02       Impact factor: 2.895

9.  Spontaneous Pneumomediastinum in an Adolescent Soccer Player.

Authors:  Akinori Kobayakawa; Hideki Hiraiwa; Shinya Ishizuka; Satoshi Yamashita; Hiroki Oba; Yusuke Kawamura; Takefumi Sakaguchi; Masaru Idota; Takahiro Haga; Takafumi Mizuno; Itaru Kawashima; Kanae Kuriyama; Shiro Imagama
Journal:  J Sports Sci Med       Date:  2021-03-01       Impact factor: 2.988

10.  Spontaneous pneumomediastinum from running sprints.

Authors:  Joseph W Turban
Journal:  Case Rep Med       Date:  2010-09-02
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