| Literature DB >> 19409942 |
Margaret Finlay1, ZhengQiang Yuan, Faith Burden, Andrew Trawford, Iain M Morgan, M Saveria Campo, Lubna Nasir.
Abstract
BPVs are double stranded DNA viruses that can infect several species other than the natural host, cattle, including equids. In equids, BPV-1, and, less commonly BPV-2, infection gives rise to fibroblastic tumours of the skin. Whilst a causal relationship between BPV-1/2 and equine sarcoids is now well established, how the disease is transmitted is not known. In this study we show BPV-1 DNA can be detected in flies trapped in the proximity of sarcoid-affected animals. Sequence analysis of the BPV-1 LCR from flies indicates that flies harbour BPV-1 LCR sequence variants II and IV which are commonly detected in equine sarcoids. These data suggest that flies may be able to transmit BPV-1 between equids.Entities:
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Year: 2009 PMID： 19409942 DOI： 10.1016/j.virusres.2009.04.015
Source DB: PubMed Journal: Virus Res ISSN： 0168-1702 Impact factor: 3.303