Literature DB >> 19409783

Binaphthyl scaffolded peptoids via ring-closing metathesis reactions and their anti-bacterial activities.

Adel Garas1, John B Bremner, Jonathan Coates, John Deadman, Paul A Keller, Stephen G Pyne, David I Rhodes.   

Abstract

An efficient synthesis of four new acyclic and four new cyclic binaphthyl-based cationic peptoids is described. These compounds had anti-bacterial activities with MIC values of 4-62 microg/mL against Staphylococcus aureus.

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Year:  2009        PMID: 19409783     DOI: 10.1016/j.bmcl.2009.04.046

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  2 in total

Review 1.  Solid-phase synthesis of N-substituted glycine oligomers (alpha-peptoids) and derivatives.

Authors:  Adrian S Culf; Rodney J Ouellette
Journal:  Molecules       Date:  2010-08-04       Impact factor: 4.411

2.  Tandem RCM-Claisen rearrangement-[2+2] cycloaddition of O,O'-(but-2-en-1,4-diyl)-bridged binaphthols.

Authors:  Michael Abraham; Wolfgang Reischl; Karl A Kirchner; Alexander Roller; Luis F Veiros; Michael Widhalm
Journal:  Molecules       Date:  2012-12-07       Impact factor: 4.411

  2 in total

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