Literature DB >> 19409260

A lethal convergence of dopamine and calcium.

D James Surmeier1.   

Abstract

The controversy about whether dopamine contributes to cell loss in Parkinson's disease takes a new turn as Mosharov et al. in this issue of Neuron demonstrate that Ca2+ influx through L-type channels elevates dopamine synthesis to potentially toxic levels in vulnerable ventral mesencephalon neurons.

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Year:  2009        PMID: 19409260     DOI: 10.1016/j.neuron.2009.04.010

Source DB:  PubMed          Journal:  Neuron        ISSN: 0896-6273            Impact factor:   17.173


  3 in total

1.  L-type calcium channel blockers and Parkinson disease in Denmark.

Authors:  Beate Ritz; Shannon L Rhodes; Lei Qian; Eva Schernhammer; Jørgen H Olsen; Søren Friis
Journal:  Ann Neurol       Date:  2010-05       Impact factor: 10.422

2.  Reduced vesicular storage of catecholamines causes progressive degeneration in the locus ceruleus.

Authors:  Tonya N Taylor; Shawn P Alter; Minzheng Wang; David S Goldstein; Gary W Miller
Journal:  Neuropharmacology       Date:  2013-09-08       Impact factor: 5.250

3.  L-type calcium channel blockers and a symptom complex mimicking de Melo-Souza's syndrome.

Authors:  Upinder Kaur; Pritam Das; Indrajeet Singh Gambhir; Sankha Shubhra Chakrabarti
Journal:  Neurol Sci       Date:  2018-12-01       Impact factor: 3.307

  3 in total

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