BACKGROUND: Salivary glands present a wide diversity in histopathologic types and biologic behaviors, thus complicating the search for prognostic factors. METHODS: We compared 2 prognostic scores that were previously published for patients with parotid carcinoma in a retrospective series of 175 patients treated in a single institution. RESULTS: Cox multivariate analysis indicated clinical skin invasion, facial nerve function, and perineural growth as the most significant recurrent disease-related prognostic factors. According to the Vander Poorten score, 148 patients were divided into 4 groups, with the 5-year disease-free survival of 76%, 81%, 69%, and 35%, respectively. In the Carrillo's score, the patients were divided into 3 groups: low-risk, intermediate-risk, and high-risk, with the 5-year disease-free survival of 84%, 73%, and 34%, respectively. CONCLUSION: Carrillo's score showed more distinct survival curves, and determination of groups with a more favorable prognosis was difficult for both scores. Therefore, both scores were not totally reproducible for our group of patients.
BACKGROUND: Salivary glands present a wide diversity in histopathologic types and biologic behaviors, thus complicating the search for prognostic factors. METHODS: We compared 2 prognostic scores that were previously published for patients with parotid carcinoma in a retrospective series of 175 patients treated in a single institution. RESULTS: Cox multivariate analysis indicated clinical skin invasion, facial nerve function, and perineural growth as the most significant recurrent disease-related prognostic factors. According to the Vander Poorten score, 148 patients were divided into 4 groups, with the 5-year disease-free survival of 76%, 81%, 69%, and 35%, respectively. In the Carrillo's score, the patients were divided into 3 groups: low-risk, intermediate-risk, and high-risk, with the 5-year disease-free survival of 84%, 73%, and 34%, respectively. CONCLUSION: Carrillo's score showed more distinct survival curves, and determination of groups with a more favorable prognosis was difficult for both scores. Therefore, both scores were not totally reproducible for our group of patients.
Authors: Rohan R Walvekar; Pedro A Andrade Filho; Raja R Seethala; William E Gooding; Dwight E Heron; Jonas T Johnson; Robert L Ferris Journal: Head Neck Date: 2011-02 Impact factor: 3.147
Authors: Boban M Erovic; Manish D Shah; Guillem Bruch; Meredith Johnston; U Johnston; John Kim; Brian O'Sullivan; Bayardo Perez-Ordonez; Ilan Weinreb; Eshetu G Atenafu; John R de Almeida; Patrick J Gullane; Dale Brown; Ralph W Gilbert; Jonathan C Irish; David P Goldstein Journal: J Otolaryngol Head Neck Surg Date: 2015-10-29