Literature DB >> 19407116

Malaria drug shortages in Kenya: a major failure to provide access to effective treatment.

Beth B Kangwana1, Julius Njogu, Beatrice Wasunna, Sarah V Kedenge, Dorothy N Memusi, Catherine A Goodman, Dejan Zurovac, Robert W Snow.   

Abstract

A key bench mark of successful therapeutic policy implementation, and thus effectiveness, is that the recommended drugs are available at the point of care. Two years after artemether-lumefathrine (AL) was introduced for the management of uncomplicated malaria in Kenya, we carried out a cross-sectional survey to investigate AL availability in government facilities in seven malaria-endemic districts. One of four of the surveyed facilities had none of the four AL weight-specific treatment packs in stock; three of four facilities were out of stock of at least one weight-specific AL pack, leading health workers to prescribe a range of inappropriate alternatives. The shortage was in large part caused by a delayed procurement process. National ministries of health and the international community must address the current shortcomings facing antimalarial drug supply to the public sector.

Entities:  

Mesh:

Substances:

Year:  2009        PMID: 19407116      PMCID: PMC2679204     

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN: 0002-9637            Impact factor:   2.345


  9 in total

Review 1.  WHO, the Global Fund, and medical malpractice in malaria treatment.

Authors:  Amir Attaran; Karen I Barnes; Christopher Curtis; Umberto d'Alessandro; Caterina I Fanello; Mary R Galinski; Gilbert Kokwaro; Sornchai Looareesuwan; Michael Makanga; Theonest K Mutabingwa; Ambrose Talisuna; Jean François Trape; William M Watkins
Journal:  Lancet       Date:  2004-01-17       Impact factor: 79.321

Review 2.  History, dynamics, and public health importance of malaria parasite resistance.

Authors:  Ambrose O Talisuna; Peter Bloland; Umberto D'Alessandro
Journal:  Clin Microbiol Rev       Date:  2004-01       Impact factor: 26.132

Review 3.  The process of changing national malaria treatment policy: lessons from country-level studies.

Authors:  Holly Ann Williams; David Durrheim; Rima Shretta
Journal:  Health Policy Plan       Date:  2004-11       Impact factor: 3.344

4.  Using evidence to change antimalarial drug policy in Kenya.

Authors:  R Shretta; J Omumbo; B Rapuoda; R W Snow
Journal:  Trop Med Int Health       Date:  2000-11       Impact factor: 2.622

Review 5.  A major transition in malaria treatment: the adoption and deployment of artemisinin-based combination therapies.

Authors:  Andrea Bosman; Kamini N Mendis
Journal:  Am J Trop Med Hyg       Date:  2007-12       Impact factor: 2.345

6.  Malaria case-management under artemether-lumefantrine treatment policy in Uganda.

Authors:  Dejan Zurovac; James K Tibenderana; Joan Nankabirwa; James Ssekitooleko; Julius N Njogu; John B Rwakimari; Sylvia Meek; Ambrose Talisuna; Robert W Snow
Journal:  Malar J       Date:  2008-09-19       Impact factor: 2.979

7.  Health facility and health worker readiness to deliver new national treatment policy for malaria in Kenya.

Authors:  J Njogu; W Akhwale; D H Hamer; D Zurovac
Journal:  East Afr Med J       Date:  2008-05

8.  The challenges of changing national malaria drug policy to artemisinin-based combinations in Kenya.

Authors:  Abdinasir A Amin; Dejan Zurovac; Beth B Kangwana; Joanne Greenfield; Dorothy N Otieno; Willis S Akhwale; Robert W Snow
Journal:  Malar J       Date:  2007-05-29       Impact factor: 2.979

9.  Paediatric malaria case-management with artemether-lumefantrine in Zambia: a repeat cross-sectional study.

Authors:  Dejan Zurovac; Mickey Ndhlovu; Nawa Sipilanyambe; Pascalina Chanda; Davidson H Hamer; Jon L Simon; Robert W Snow
Journal:  Malar J       Date:  2007-03-16       Impact factor: 2.979

  9 in total
  54 in total

1.  The magnitude and trend of artemether-lumefantrine stock-outs at public health facilities in Kenya.

Authors:  Raymond K Sudoi; Sophie Githinji; Andrew Nyandigisi; Alex Muturi; Robert W Snow; Dejan Zurovac
Journal:  Malar J       Date:  2012-02-08       Impact factor: 2.979

2.  Drug procurement, the Global Fund and misguided competition policies.

Authors:  Richard Tren; Kimberly Hess; Roger Bate
Journal:  Malar J       Date:  2009-12-22       Impact factor: 2.979

3.  Alterations in Plasmodium falciparum genetic structure two years after increased malaria control efforts in western Kenya.

Authors:  Anne M Vardo-Zalik; Guofa Zhou; Daibin Zhong; Yaw A Afrane; Andrew K Githeko; Guiyun Yan
Journal:  Am J Trop Med Hyg       Date:  2012-11-19       Impact factor: 2.345

4.  A reversal in reductions of child mortality in western Kenya, 2003-2009.

Authors:  Mary J Hamel; Kubaje Adazu; David Obor; Maquins Sewe; John Vulule; John M Williamson; Laurence Slutsker; Daniel R Feikin; Kayla F Laserson
Journal:  Am J Trop Med Hyg       Date:  2011-10       Impact factor: 2.345

5.  Barriers to prompt and effective malaria treatment among the poorest population in Kenya.

Authors:  Jane Chuma; Vincent Okungu; Catherine Molyneux
Journal:  Malar J       Date:  2010-05-27       Impact factor: 2.979

6.  Changing malaria intervention coverage, transmission and hospitalization in Kenya.

Authors:  Emelda A Okiro; Victor A Alegana; Abdisalan M Noor; Robert W Snow
Journal:  Malar J       Date:  2010-10-15       Impact factor: 2.979

7.  Malaria paediatric hospitalization between 1999 and 2008 across Kenya.

Authors:  Emelda A Okiro; Victor A Alegana; Abdisalan M Noor; Juliette J Mutheu; Elizabeth Juma; Robert W Snow
Journal:  BMC Med       Date:  2009-12-09       Impact factor: 8.775

8.  Time for a "Third Wave" of malaria activism to tackle the drug stock-out crisis.

Authors: 
Journal:  PLoS Med       Date:  2009-11-24       Impact factor: 11.069

9.  Health service providers in Somalia: their readiness to provide malaria case-management.

Authors:  Abdisalan M Noor; Ismail A Rage; Bruno Moonen; Robert W Snow
Journal:  Malar J       Date:  2009-05-13       Impact factor: 2.979

Review 10.  Addressing antimicrobial resistance by improving access and quality of care-A review of the literature from East Africa.

Authors:  Kathrin Loosli; Alicia Davis; Adrian Muwonge; Tiziana Lembo
Journal:  PLoS Negl Trop Dis       Date:  2021-07-22
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.