Literature DB >> 1940662

Selection and mutation at a diallelic X-linked locus.

J M Szucs1.   

Abstract

Equilibria and convergence of gene frequencies are studied in the case of a diallelic X-linked locus under the influence of selection and mutation. The model used is that of an infinite diploid population with nonoverlapping discrete generations and random mating. It is proved that if the mutation rates and fitnesses are constant and the mutation rates are less than one-third, then global convergence of gene frequencies to equilibria occurs. The phase portraits of the dynamical system describing the change of allelic frequencies from one generation to the next are determined. Convergence of gene frequencies is monotone from a certain generation on if every other generation is skipped. In the case without mutation, our proof of this monotone convergence simplifies G. Palm's original proof.

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Year:  1991        PMID: 1940662     DOI: 10.1007/bf00163915

Source DB:  PubMed          Journal:  J Math Biol        ISSN: 0303-6812            Impact factor:   2.259


  14 in total

1.  Stable equilibrium at a sex-linked locus.

Authors:  S P MANDEL
Journal:  Nature       Date:  1959-05-09       Impact factor: 49.962

2.  The mutation rate of the gene for haemophilia, and its segregation ratios in males and females.

Authors:  J B S HALDANE
Journal:  Ann Eugen       Date:  1947-06

3.  Convergence to equilibrium in a genetic model with differential viability between the sexes.

Authors:  J F Selgrade; M Ziehe
Journal:  J Math Biol       Date:  1987       Impact factor: 2.259

4.  Continuous selective models.

Authors:  T Nagylaki; J F Crow
Journal:  Theor Popul Biol       Date:  1974-04       Impact factor: 1.570

5.  Continuous selective models with mutation and migration.

Authors:  T Nagylaki
Journal:  Theor Popul Biol       Date:  1974-04       Impact factor: 1.570

6.  The maximization of average fitness by natural selection for a sex-linked locus.

Authors:  C C Li
Journal:  Proc Natl Acad Sci U S A       Date:  1967-05       Impact factor: 11.205

7.  Selection in dioecious populations.

Authors:  T Nagylaki
Journal:  Ann Hum Genet       Date:  1979-10       Impact factor: 1.670

8.  Stable cycling in discrete-time genetic models.

Authors:  A Hastings
Journal:  Proc Natl Acad Sci U S A       Date:  1981-11       Impact factor: 11.205

9.  The selection mutation equation.

Authors:  J Hofbauer
Journal:  J Math Biol       Date:  1985       Impact factor: 2.259

10.  Fundamental theorem of natural selection.

Authors:  C C Li
Journal:  Nature       Date:  1967-04-29       Impact factor: 49.962

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  1 in total

1.  Selection-mutation at a diallelic autosomal locus in a dioecious population.

Authors:  J M Szucs
Journal:  J Math Biol       Date:  1991       Impact factor: 2.259

  1 in total

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