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Literature DB >> 19404335

Smurf1 zaps the talin head.

Abstract

Focal adhesion turnover is essential for cell migration. New results show that the talin head liberated from talin by calpain II cleavage has a key role in these events, and that its levels are tightly regulated by Smurf1-mediated ubiquitylation counteracted by Cdk5-mediated phosphorylation.

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Year: 2009 PMID： 19404335 DOI： 10.1038/ncb0509-538

Source DB: PubMed Journal: Nat Cell Biol ISSN： 1465-7392 Impact factor: 28.824

15 in total

1. Talin phosphorylation sites mapped by mass spectrometry.

Authors: Boris Ratnikov; Celeste Ptak; Jaewon Han; Jeffrey Shabanowitz; Donald F Hunt; Mark H Ginsberg
Journal: J Cell Sci Date: 2005-11-01 Impact factor: 5.285

2. Structural basis of integrin activation by talin.

Authors: Kate L Wegener; Anthony W Partridge; Jaewon Han; Andrew R Pickford; Robert C Liddington; Mark H Ginsberg; Iain D Campbell
Journal: Cell Date: 2007-01-12 Impact factor: 41.582

3. The talin rod IBS2 alpha-helix interacts with the beta3 integrin cytoplasmic tail membrane-proximal helix by establishing charge complementary salt bridges.

Authors: Sophie Rodius; Olivier Chaloin; Michèle Moes; Elisabeth Schaffner-Reckinger; Isabelle Landrieu; Guy Lippens; Minghui Lin; Ji Zhang; Nelly Kieffer
Journal: J Biol Chem Date: 2008-06-23 Impact factor: 5.157

4. RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences.

Authors: Ho-Sup Lee; Chinten James Lim; Wilma Puzon-McLaughlin; Sanford J Shattil; Mark H Ginsberg
Journal: J Biol Chem Date: 2008-12-19 Impact factor: 5.157

5. Structural basis for the autoinhibition of talin in regulating integrin activation.

Authors: Esen Goksoy; Yan-Qing Ma; Xiaoxia Wang; Xiangming Kong; Dhanuja Perera; Edward F Plow; Jun Qin
Journal: Mol Cell Date: 2008-07-11 Impact factor: 17.970

6. Epidermal growth factor activates m-calpain (calpain II), at least in part, by extracellular signal-regulated kinase-mediated phosphorylation.

Authors: A Glading; R J Bodnar; I J Reynolds; H Shiraha; L Satish; D A Potter; H C Blair; A Wells
Journal: Mol Cell Biol Date: 2004-03 Impact factor: 4.272

7. Talin depletion reveals independence of initial cell spreading from integrin activation and traction.

Authors: Xian Zhang; Guoying Jiang; Yunfei Cai; Susan J Monkley; David R Critchley; Michael P Sheetz
Journal: Nat Cell Biol Date: 2008-09 Impact factor: 28.824

8. Stretching single talin rod molecules activates vinculin binding.

Authors: Armando del Rio; Raul Perez-Jimenez; Ruchuan Liu; Pere Roca-Cusachs; Julio M Fernandez; Michael P Sheetz
Journal: Science Date: 2009-01-30 Impact factor: 63.714

9. Talin phosphorylation by Cdk5 regulates Smurf1-mediated talin head ubiquitylation and cell migration.

Authors: Cai Huang; Zenon Rajfur; Nima Yousefi; Zaozao Chen; Ken Jacobson; Mark H Ginsberg
Journal: Nat Cell Biol Date: 2009-04-12 Impact factor: 28.824

10. Structural determinants of integrin binding to the talin rod.

Authors: Alexandre R Gingras; Wolfgang H Ziegler; Andrey A Bobkov; M Gordon Joyce; Domenico Fasci; Mirko Himmel; Sven Rothemund; Anett Ritter; J Günter Grossmann; Bipin Patel; Neil Bate; Benjamin T Goult; Jonas Emsley; Igor L Barsukov; Gordon C K Roberts; Robert C Liddington; Mark H Ginsberg; David R Critchley
Journal: J Biol Chem Date: 2009-01-27 Impact factor: 5.157

4 in total