Literature DB >> 19403317

Epithelial salivary tumors in Sri Lanka: a retrospective study of 713 cases.

Wanninayake Mudiyanselage Tilakaratne1, Primali Rukmal Jayasooriya, Tennakoon Mudiyanselage Priyanka Bandara Tennakoon, Takashi Saku.   

Abstract

OBJECTIVE: The aim of this retrospective study was to evaluate the clinicopathologic data to determine the distribution of epithelial salivary tumors, especially minor salivary tumors, in Sri Lanka.
MATERIALS AND METHODS: A total of 713 salivary tumors diagnosed at the Department of Oral Pathology, during the period from 1990 to 2007 were reviewed.
RESULTS: Out of the 713 epithelial salivary tumors, 356 (49.9%) were classified as benign and 357 (50.1%) as malignant, indicating a benign-to-malignant ratio of 1:1. The majority of both benign (29%) and malignant (39%) tumors occurred in the minor salivary glands. Malignant tumors were slightly more common in minor salivary glands, indicating a benign-to-malignant ratio of 1:0.75. Among the minor salivary sites, palate was the most frequent location, accounting for 51% of the tumors (246 out of 486). The tumors affected adult patients more commonly, and a slight female predominance (1:1.15) was also evident. Pleomorphic adenoma was the most frequent tumor, representing 38% of all tumors (274 out of 713), followed by mucoepidermoid carcinoma 21.6% (154 out of 713) and adenoid cystic carcinoma 13.5% (96 out of 713). The commonest benign and malignant tumors were pleomorphic adenoma and mucoepidermoid carcinoma in both major and minor salivary glands.
CONCLUSION: According to the findings of this study, equal frequencies of benign and malignant tumors indicate higher occurrences of malignancies, especially in the minor salivary glands, in the Sri Lankan population.

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Year:  2009        PMID: 19403317     DOI: 10.1016/j.tripleo.2009.01.026

Source DB:  PubMed          Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod        ISSN: 1079-2104


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