Literature DB >> 1940322

Expression of transforming growth factor beta 1 in the submandibular gland of the rat.

O Amano1, T Tsuji, T Nakamura, S Iseki.   

Abstract

We employed immunocytochemical and in situ hybridization techniques to study the expression of transforming growth factor beta 1 (TGF-beta 1) in rat submandibular gland. Immunoreactivity for TGF-beta 1 was observed in the cells of granular convoluted tubules (GCTs), striated ducts, and excretory ducts, whereas it was absent in the intercalated ducts and secretory acini in both male and female rats. Immunoelectron microscopy revealed the ultrastructural localization of TGF-beta 1 in the secretory granules of GCT cells. On the other hand, signals for rat TGF-beta 1 mRNA were abundant in the GCT and striated duct cells but were lacking in the excretory duct cells. These results provided evidence for the production of TGF-beta 1 in the GCTs and striated ducts of rat submandibular gland.

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Year:  1991        PMID： 1940322     DOI： 10.1177/39.12.1940322

Source DB:  PubMed          Journal:  J Histochem Cytochem        ISSN： 0022-1554            Impact factor:   2.479


  8 in total

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2.  Conditional overexpression of TGF-beta1 disrupts mouse salivary gland development and function.

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4.  Submandibular gland peptide-T (SGP-T) inhibits intestinal anaphylaxis.

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5.  Basic fibroblast growth factor in rat salivary glands.

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6.  Immunohistochemical localization of transforming growth factor alpha in the major salivary glands of male and female rats.

Authors:  H H Wu; H Kawamata; D D Wang; R Oyasu
Journal:  Histochem J       Date:  1993-09

7.  Selective localization of diacylglycerol kinase (DGK)ζ in the terminal tubule cells in the submandibular glands of early postnatal mice.

Authors:  Wiphawi Hipkaeo; Surang Chomphoo; Sawetree Pakkarato; Waraporn Sakaew; Tarinee Sawatpanich; Yasukazu Hozumi; Yada Polsan; Damrong Hipkaeo; Kaoru Goto; Hisatake Kondo
Journal:  Histochem Cell Biol       Date:  2015-05-08       Impact factor: 4.304

8.  Anatomy and histology of rodent and human major salivary glands: -overview of the Japan salivary gland society-sponsored workshop-.

Authors:  Osamu Amano; Kenichi Mizobe; Yasuhiko Bando; Koji Sakiyama
Journal:  Acta Histochem Cytochem       Date:  2012-09-22       Impact factor: 1.938
  8 in total

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