OBJECTIVE: To describe a case of resumption of ovarian function 20 years after chemotherapy-induced ovarian failure. DESIGN: Case report. SETTING: University teaching hospital. PATIENT(S): A 33-year-old nulliparous black woman. INTERVENTION(S): Progesterone challenge, transvaginal ultrasound (TVS). MAIN OUTCOME MEASURE(S): Estradiol and FSH hormone levels. RESULT(S): Confirmation that ovarian function returned in a women who presented with cyclic vaginal bleeding after a 20-year history of amenorrhea secondary to chemotherapy-induced ovarian failure. CONCLUSION(S): Return of ovarian function is possible after prolonged periods in women with chemotherapy-induced ovarian failure.
OBJECTIVE: To describe a case of resumption of ovarian function 20 years after chemotherapy-induced ovarian failure. DESIGN: Case report. SETTING: University teaching hospital. PATIENT(S): A 33-year-old nulliparous black woman. INTERVENTION(S): Progesterone challenge, transvaginal ultrasound (TVS). MAIN OUTCOME MEASURE(S): Estradiol and FSH hormone levels. RESULT(S): Confirmation that ovarian function returned in a women who presented with cyclic vaginal bleeding after a 20-year history of amenorrhea secondary to chemotherapy-induced ovarian failure. CONCLUSION(S): Return of ovarian function is possible after prolonged periods in women with chemotherapy-induced ovarian failure.