Literature DB >> 19402084

Platinum(II)-catalyzed intramolecular cyclization of o-substituted aryl alkynes through sp3 C-H activation.

Shangdong Yang1, Zigang Li, Xing Jian, Chuan He.   

Abstract

Ring leader: PtCl(2) catalyzes intramolecular cyclization of o-isopropyl or o-benzyl aryl alkynes to give substituted indene derivatives with good yields and high selectivity. This reaction appears to proceed through an sp(3) C-H activation and 1,4-hydrogen migration pathway (see scheme).

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Year:  2009        PMID： 19402084     DOI： 10.1002/anie.200900368

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  3 in total

1.  C-H bond functionalization via hydride transfer: formation of α-arylated piperidines and 1,2,3,4-tetrahydroisoquinolines via stereoselective intramolecular amination of benzylic C-H bonds.

Authors:  Paul A Vadola; Ignacio Carrera; Dalibor Sames
Journal:  J Org Chem       Date:  2012-06-06       Impact factor: 4.354

2.  C-H bond functionalization via hydride transfer: direct coupling of unactivated alkynes and sp(3) C-H bonds catalyzed by platinum tetraiodide.

Authors:  Paul A Vadola; Dalibor Sames
Journal:  J Am Chem Soc       Date:  2009-11-18       Impact factor: 15.419

3.  Divergent C-H Insertion-Cyclization Cascades of N-Allyl Ynamides.

Authors:  Holly V Adcock; Elli Chatzopoulou; Paul W Davies
Journal:  Angew Chem Int Ed Engl       Date:  2015-10-30       Impact factor: 15.336
  3 in total

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