Literature DB >> 19401186

Electric light causes cancer? Surely you're joking, Mr. Stevens.

Richard G Stevens1.   

Abstract

Night is no longer dark in the modern world, and the Milky Way has disappeared. Electric light has benefits but there are also a few detriments. These are (1) loss of the night sky, (2) wasted energy, (3) harm to animal and plant life, (4) and perhaps increases in some severe human maladies such as cancers of breast and prostate. The science on phototransduction for the circadian system and on clock gene function is evolving rapidly, and it provides a rationale for the idea that circadian disruption from light at night could cause disease. Direct evidence from humans and rodent models has also accumulated to the point where the idea is no longer fanciful. Although it may seem logical now, the journey on the path from electric light to breast cancer has been a tortuous one, at least for me.

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Year:  2009        PMID: 19401186     DOI: 10.1016/j.mrrev.2009.01.003

Source DB:  PubMed          Journal:  Mutat Res        ISSN: 0027-5107            Impact factor:   2.433


  11 in total

1.  Light at night and breast cancer risk: results from a population-based case-control study in Connecticut, USA.

Authors:  Qian Li; Tongzhang Zheng; Theodore R Holford; Peter Boyle; Yawei Zhang; Min Dai
Journal:  Cancer Causes Control       Date:  2010-10-07       Impact factor: 2.506

2.  Light aversion in mice depends on nonimage-forming irradiance detection.

Authors:  Stewart Thompson; Ana Recober; Timothy W Vogel; Adisa Kuburas; Jessica A Owens; Val C Sheffield; Andrew F Russo; Edwin M Stone
Journal:  Behav Neurosci       Date:  2010-12       Impact factor: 1.912

Review 3.  Circadian disruption, sleep loss, and prostate cancer risk: a systematic review of epidemiologic studies.

Authors:  Lara G Sigurdardottir; Unnur A Valdimarsdottir; Katja Fall; Jennifer R Rider; Steven W Lockley; Eva Schernhammer; Lorelei A Mucci
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2012-05-07       Impact factor: 4.254

Review 4.  Sirtuins, melatonin and circadian rhythms: building a bridge between aging and cancer.

Authors:  Brittney Jung-Hynes; Russel J Reiter; Nihal Ahmad
Journal:  J Pineal Res       Date:  2010-01       Impact factor: 13.007

Review 5.  Electric light, particularly at night, disrupts human circadian rhythmicity: is that a problem?

Authors:  Richard G Stevens; Yong Zhu
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2015-05-05       Impact factor: 6.237

Review 6.  Breast cancer and circadian disruption from electric lighting in the modern world.

Authors:  Richard G Stevens; George C Brainard; David E Blask; Steven W Lockley; Mario E Motta
Journal:  CA Cancer J Clin       Date:  2013-12-24       Impact factor: 508.702

7.  Epigenetic impact of long-term shiftwork: pilot evidence from circadian genes and whole-genome methylation analysis.

Authors:  Yong Zhu; Richard G Stevens; Aaron E Hoffman; Anne Tjonneland; Ulla B Vogel; Tongzhang Zheng; Johnni Hansen
Journal:  Chronobiol Int       Date:  2011-12       Impact factor: 2.877

8.  Regression of early diabetic macular oedema is associated with prevention of dark adaptation.

Authors:  G B Arden; S Jyothi; C H Hogg; Y F Lee; S Sivaprasad
Journal:  Eye (Lond)       Date:  2011-10-21       Impact factor: 3.775

9.  A cross-sectional analysis of light at night, neighborhood sociodemographics and urinary 6-sulfatoxymelatonin concentrations: implications for the conduct of health studies.

Authors:  Susan Hurley; David O Nelson; Erika Garcia; Robert Gunier; Andrew Hertz; Peggy Reynolds
Journal:  Int J Health Geogr       Date:  2013-08-30       Impact factor: 3.918

10.  Expression of phosphodiesterase 6 (PDE6) in human breast cancer cells.

Authors:  Hongli Dong; Kevin P Claffey; Stefan Brocke; Paul M Epstein
Journal:  Springerplus       Date:  2013-12-18
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