INTRODUCTION AND OBJECTIVES: The objective of this study was to determine whether a home-based intervention can reduce mortality and hospital readmissions and improve quality of life in patients with heart failure. METHODS: A randomized clinical trial was carried out between January 2004 and October 2006. In total, 283 patients admitted to hospital with a diagnosis of heart failure were randomly allocated to a home-based intervention (intervention group) or usual care (control group). The primary end-point was the combination of all-cause mortality and hospital readmission for worsening heart failure at 1-year follow-up. RESULTS: The primary end-point was observed in 41.7% of patients in the intervention group and in 54.3% in the control group. The hazard ratio was 0.70 (95% confidence interval [CI] 0.55-0.99). Taking significant clinical variables into account slightly reduced the hazard ratio to 0.62 (95% CI 0.50-0.87). At the end of the study, the quality of life of patients in the intervention group was better than in the control group (18.57 vs. 31.11; P< .001). CONCLUSIONS: A home-based intervention for patients with heart failure reduced the aggregate of mortality and hospital readmissions and improved quality of life.
RCT Entities:
INTRODUCTION AND OBJECTIVES: The objective of this study was to determine whether a home-based intervention can reduce mortality and hospital readmissions and improve quality of life in patients with heart failure. METHODS: A randomized clinical trial was carried out between January 2004 and October 2006. In total, 283 patients admitted to hospital with a diagnosis of heart failure were randomly allocated to a home-based intervention (intervention group) or usual care (control group). The primary end-point was the combination of all-cause mortality and hospital readmission for worsening heart failure at 1-year follow-up. RESULTS: The primary end-point was observed in 41.7% of patients in the intervention group and in 54.3% in the control group. The hazard ratio was 0.70 (95% confidence interval [CI] 0.55-0.99). Taking significant clinical variables into account slightly reduced the hazard ratio to 0.62 (95% CI 0.50-0.87). At the end of the study, the quality of life of patients in the intervention group was better than in the control group (18.57 vs. 31.11; P< .001). CONCLUSIONS: A home-based intervention for patients with heart failure reduced the aggregate of mortality and hospital readmissions and improved quality of life.
Authors: Andrew Sherwood; Christopher M O'Connor; Faye S Routledge; Alan L Hinderliter; Lana L Watkins; Michael A Babyak; Gary G Koch; Kirkwood F Adams; Carla Sueta Dupree; Patricia P Chang; Benson M Hoffman; Julie Johnson; Margaret Bowers; Kristy S Johnson; James A Blumenthal Journal: J Card Fail Date: 2011-01-21 Impact factor: 5.712
Authors: Carlos Rodríguez Pascual; Emilio Paredes Galán; Jose Luis Gonzalez Guerrero; Rocio Menendez Colino; Pedro Abizanda Soler; Mercedes Hornillos Calvo; Juan Jose Solano Jaurieta; Jorge Manzarbeitia Arambarri; Jose Manuel Ribera Casado; Fernando Rodríguez-Artalejo Journal: BMC Public Health Date: 2011-08-05 Impact factor: 3.295
Authors: Linda Long; Ify R Mordi; Charlene Bridges; Viral A Sagar; Edward J Davies; Andrew Js Coats; Hasnain Dalal; Karen Rees; Sally J Singh; Rod S Taylor Journal: Cochrane Database Syst Rev Date: 2019-01-29
Authors: Rod S Taylor; Viral A Sagar; Ed J Davies; Simon Briscoe; Andrew J S Coats; Hayes Dalal; Fiona Lough; Karen Rees; Sally Singh Journal: Cochrane Database Syst Rev Date: 2014-04-27