Literature DB >> 19400411

Pregnancy outcome after treatment of cervical intraepithelial neoplasia by the loop electrosurgical excision procedure and cold knife conization.

M A Michelin1, L M Merino, C A Franco, E F C Murta.   

Abstract

PURPOSE OF INVESTIGATION: The aim of this study was to evaluate the effect of LEEP and cold-knife conization on the outcome of subsequent pregnancy in a tertiary public hospital.
METHODS: One hundred and ninety-nine patients met the inclusion criteria (age between 18 and 45 years old). Cold-knife conization, LEEP, and both (conization and LEEP) were performed in 102 (51.3%), 95 (47.7%) and two (1%) women, respectively. Average ages were respectively, 33 +/- 7.3; 25 +/- 6.73 and 30 +/- 2.8.
RESULTS: Pregnancies occurred 2.6 and 4.8 years after LEEP and conization, respectively. Miscarriages and preterm pregnancies were more frequent in conization cases versus LEEP, 26% and 5.2%, 23% and 5.5%, respectively.
CONCLUSION: If patients express a desire for pregnancy, LEEP should be the procedure of choice.

Entities:  

Mesh:

Year:  2009        PMID: 19400411

Source DB:  PubMed          Journal:  Clin Exp Obstet Gynecol        ISSN: 0390-6663            Impact factor:   0.146


  4 in total

1.  Pregnancy outcome after cervical conization: risk factors for preterm delivery and the efficacy of prophylactic cerclage.

Authors:  Ka Hyun Nam; Ja Young Kwon; Young-Han Kim; Yong-Won Park
Journal:  J Gynecol Oncol       Date:  2010-12-31       Impact factor: 4.401

2.  Meta-analysis of cold-knife conization versus loop electrosurgical excision procedure for cervical intraepithelial neoplasia.

Authors:  Yan-Ming Jiang; Chang-Xian Chen; Li Li
Journal:  Onco Targets Ther       Date:  2016-06-29       Impact factor: 4.147

Review 3.  Fertility and early pregnancy outcomes after conservative treatment for cervical intraepithelial neoplasia.

Authors:  Maria Kyrgiou; Anita Mitra; Marc Arbyn; Maria Paraskevaidi; Antonios Athanasiou; Pierre P L Martin-Hirsch; Phillip Bennett; Evangelos Paraskevaidis
Journal:  Cochrane Database Syst Rev       Date:  2015-09-29

Review 4.  Adverse obstetric outcomes after local treatment for cervical preinvasive and early invasive disease according to cone depth: systematic review and meta-analysis.

Authors:  Maria Kyrgiou; Antonios Athanasiou; Maria Paraskevaidi; Anita Mitra; Ilkka Kalliala; Pierre Martin-Hirsch; Marc Arbyn; Phillip Bennett; Evangelos Paraskevaidis
Journal:  BMJ       Date:  2016-07-28
  4 in total

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