Literature DB >> 19399352

Adult rats exposed to low-doses of di-n-butyl phthalate during gestation exhibit decreased grooming behavior.

Hideo Hoshi1, Teruya Ohtsuka.   

Abstract

Developmental neurotoxicity of low-dose di-n-butyl phthalate (DBP) to rats was studied. Pregnant rats were orally given DBP at doses less than 1.0 mg/kg/day during gestation period. The body weight of all dams and their offspring as well as the offspring's motor function showed no significant adverse effect. At 21 weeks, behaviors of male rats were examined by placing into a test cage. The rats born from dams exposed to 10 microg DBP/kg/day exhibited a significant decrease of grooming. This indicates low-dose DBP adversely affects emotional stability in a novel environment.

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Year:  2009        PMID： 19399352     DOI： 10.1007/s00128-009-9729-1

Source DB:  PubMed          Journal:  Bull Environ Contam Toxicol        ISSN： 0007-4861            Impact factor:   2.151


  7 in total

1.  Effects of Perinatal Exposure to Phthalates and a High-Fat Diet on Maternal Behavior and Pup Development and Social Play.

Authors:  Daniel G Kougias; Laura R Cortes; Laura Moody; Steven Rhoads; Yuan-Xiang Pan; Janice M Juraska
Journal:  Endocrinology       Date:  2018-02-01       Impact factor: 4.736

2.  Paternal and maternal preconception urinary phthalate metabolite concentrations and child behavior.

Authors:  Carmen Messerlian; David Bellinger; Lidia Mínguez-Alarcón; Megan E Romano; Jennifer B Ford; Paige L Williams; Antonia M Calafat; Russ Hauser; Joseph M Braun
Journal:  Environ Res       Date:  2017-07-21       Impact factor: 6.498

3.  Prenatal exposure to bisphenol A and phthalates and infant neurobehavior.

Authors:  Kimberly Yolton; Yingying Xu; Donna Strauss; Mekibib Altaye; Antonia M Calafat; Jane Khoury
Journal:  Neurotoxicol Teratol       Date:  2011-08-10       Impact factor: 3.763

Review 4.  Autistic-like traits in laboratory rodents exposed to phthalic acid esters during early development - an animal model of autism?

Authors:  M Morová; L Kršková
Journal:  Physiol Res       Date:  2021-05-12       Impact factor: 1.881

5.  Prenatal Exposure to Nonpersistent Endocrine Disruptors and Behavior in Boys at 3 and 5 Years.

Authors:  Claire Philippat; Dorothy Nakiwala; Antonia M Calafat; Jérémie Botton; Maria De Agostini; Barbara Heude; Rémy Slama
Journal:  Environ Health Perspect       Date:  2017-09-15       Impact factor: 9.031

6.  Prenatal exposure to a wide range of environmental chemicals and child behaviour between 3 and 7 years of age - An exposome-based approach in 5 European cohorts.

Authors:  Paulina Jedynak; Léa Maitre; Mónica Guxens; Kristine B Gützkow; Jordi Julvez; Mónica López-Vicente; Jordi Sunyer; Maribel Casas; Leda Chatzi; Regina Gražulevičienė; Mariza Kampouri; Rosie McEachan; Mark Mon-Williams; Ibon Tamayo; Cathrine Thomsen; José Urquiza; Marina Vafeiadi; John Wright; Xavier Basagaña; Martine Vrijheid; Claire Philippat
Journal:  Sci Total Environ       Date:  2020-12-15       Impact factor: 7.963

7.  Phthalates induce neurotoxicity affecting locomotor and thermotactic behaviors and AFD neurons through oxidative stress in Caenorhabditis elegans.

Authors:  I-Ling Tseng; Ying-Fei Yang; Chan-Wei Yu; Wen-Hsuan Li; Vivian Hsiu-Chuan Liao
Journal:  PLoS One       Date:  2013-12-12       Impact factor: 3.240
  7 in total

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