Literature DB >> 19398803

Botulinum toxin type A for rehabilitation after a spinal cord injury: a case report.

A S Naicker1, S A Roohi, J L L Chan.   

Abstract

A 56-year-old man became quadriplegic, bed bound, and carer-dependent secondary to cervical osteomyelitis. Three years later, he presented with generalised spasticity, crouched posture, and a large sacral pressure sore. The severe spasticity in his hips and knees prevented ischial sitting. Injections of botulinum toxin type A to both hamstrings and gastrosoleuii controlled the flexor spasticity of his lower limbs and facilitated rehabilitation and wound healing through proper positioning, wound care, stretching, and weight-bearing exercises. A few weeks later, the patient could better position himself in bed (prone lying) and on his wheelchair (ischial sitting). His spasm-related pain lessened and his mobility and activities of daily living improved. The sacral pressure sore healed completely a few months later. The patient could sleep better, feed with set-up and adaptive aids, groom, dress, and transfer himself with minimal assistance. The effects of botulinum toxin extended beyond just spasticity reduction. His upper extremity function, mobility, and social well-being were all improved through better positioning.

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Year:  2009        PMID: 19398803     DOI: 10.1177/230949900901700121

Source DB:  PubMed          Journal:  J Orthop Surg (Hong Kong)        ISSN: 1022-5536            Impact factor:   1.118


  8 in total

1.  Botulinum toxin type A combined with neurodynamic mobilization for lower limb spasticity: a case report.

Authors:  Jorge H Villafañe
Journal:  J Chiropr Med       Date:  2013-03

2.  Botulinum toxin type A in the healing of chronic lesion following bilateral spasticity of gluteus muscle.

Authors:  Emanuele Cigna; Michele Maruccia; Benedetta Fanelli; Nicolò Scuderi
Journal:  Int Wound J       Date:  2012-10-19       Impact factor: 3.315

3.  Treatment of spasticity in spinal cord injury with botulinum toxin.

Authors:  Ramiro Palazón-García; Mónica Alcobendas-Maestro; Ana Esclarin-de Ruz; Ana María Benavente-Valdepeñas
Journal:  J Spinal Cord Med       Date:  2018-06-05       Impact factor: 1.985

4.  Kinetic and reaction pathway analysis in the application of botulinum toxin a for wound healing.

Authors:  Frank J Lebeda; Zygmunt F Dembek; Michael Adler
Journal:  J Toxicol       Date:  2011-11-24

Review 5.  Botulinum Toxin and Neuronal Regeneration after Traumatic Injury of Central and Peripheral Nervous System.

Authors:  Siro Luvisetto
Journal:  Toxins (Basel)       Date:  2020-07-02       Impact factor: 4.546

Review 6.  Botulinum Toxin: From Poison to Possible Treatment for Spasticity in Spinal Cord Injury.

Authors:  Ramiro Palazón-García; Ana María Benavente-Valdepeñas
Journal:  Int J Mol Sci       Date:  2021-05-05       Impact factor: 5.923

7.  Antispastic therapy with botulinum toxin type A in patients with traumatic spinal cord lesion.

Authors:  Ulrich J Spiegl; Doris Maier; Oliver Gonschorek; Christoph-Eckhard Heyde; Volker Bühren
Journal:  GMS Interdiscip Plast Reconstr Surg DGPW       Date:  2014-12-10

8.  Can Botulinum Toxin Type A effectively treat neuropathic pain in spinal cord injury?: A protocol of systematic review and meta-analysis.

Authors:  Zeng-Mian Wang; Ze-Yu Wang; Chun-Jie Wei; Yao-Jia Jiang
Journal:  Medicine (Baltimore)       Date:  2020-06-19       Impact factor: 1.817

  8 in total

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