Literature DB >> 19397400

Analysis of the V1V2 region of the SIV envelope in the brains of morphine-dependent and control SIV/SHIV-infected macaques.

Vanessa Rivera-Amill1, Richard J Noel, Ivelisse Rivera Román, Yashira García Flores, Shilpa Buch, Anil Kumar.   

Abstract

Six morphine-dependent and three control macaques were infected with a mixture of SIV/SHIV. Half of the animals in the morphine group developed accelerated disease (rapid progressor) and died within 20 weeks postinfection. The evolution of the envelope gene in the brain of the rapid progressor and morphine-dependent group along with that in the control group was assessed. Six to 10 clones from the brain of each macaque were sequenced and were compared against each other as well as against a challenge virus. Analysis of the sequences revealed that the diversity and divergence of the clones were higher in the control group as compared to the morphine-dependent macaques, although this difference was not statistically significant.

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Year:  2009        PMID： 19397400      PMCID： PMC2853860          DOI： 10.1089/aid.2008.0279

Source DB:  PubMed          Journal:  AIDS Res Hum Retroviruses        ISSN： 0889-2229            Impact factor:   2.205


  23 in total

1.  Effect of opioids on oral Salmonella infection and immune function.

Authors:  L K Eisenstein; A S MacFarland; X Peng; M E Hilburger; R T Rahim; L J Meissler; T J Rogers; A C Wan; M W Adler
Journal:  Adv Exp Med Biol       Date:  2001       Impact factor: 2.622

2.  SIV Vpr evolution is inversely related to disease progression in a morphine-dependent rhesus macaque model of AIDS.

Authors:  Richard J Noel; Anil Kumar
Journal:  Virology       Date:  2006-10-24       Impact factor: 3.616

3.  Chronic morphine exposure causes pronounced virus replication in cerebral compartment and accelerated onset of AIDS in SIV/SHIV-infected Indian rhesus macaques.

Authors:  Rakesh Kumar; Suheydi Orsoni; Lisa Norman; Ashish S Verma; Grissell Tirado; Luis D Giavedoni; Silvija Staprans; Gregory M Miller; Shilpa J Buch; Anil Kumar
Journal:  Virology       Date:  2006-07-28       Impact factor: 3.616

4.  Variable region 4 of SIV envelope correlates with rapid disease progression in morphine-exposed macaques infected with SIV/SHIV.

Authors:  Vanessa Rivera-Amill; Richard J Noel; Suheydi Orsini; Griselle Tirado; José M García; Shilpa Buch; Anil Kumar
Journal:  Virology       Date:  2006-09-28       Impact factor: 3.616

5.  Correlation between SIV Tat evolution and AIDS progression in cerebrospinal fluid of morphine-dependent and control macaques infected with SIV and SHIV.

Authors:  Richard J Noel; Ziomara Marrero-Otero; Rakesh Kumar; Gladys S Chompre-González; Ashish S Verma; Anil Kumar
Journal:  Virology       Date:  2006-04-27       Impact factor: 3.616

Review 6.  HIV-1 infection in injection drug users.

Authors:  Jonathan Allen Cohn
Journal:  Infect Dis Clin North Am       Date:  2002-09       Impact factor: 5.982

7.  Morphine enhances HIV infection of neonatal macrophages.

Authors:  Yuan Li; Jeffrey D Merrill; Kathy Mooney; Li Song; Xu Wang; Chang-Jiang Guo; Rashmin C Savani; David S Metzger; Steven D Douglas; Wen-Zhe Ho
Journal:  Pediatr Res       Date:  2003-05-07       Impact factor: 3.756

8.  Methamphetamine enhances HIV infection of macrophages.

Authors:  Hao Liang; Xu Wang; Hui Chen; Li Song; Li Ye; Shi-Hong Wang; Yan-Jian Wang; Lin Zhou; Wen-Zhe Ho
Journal:  Am J Pathol       Date:  2008-05-05       Impact factor: 4.307

Review 9.  Opiates, immune system, acquired immunodeficiency syndrome, and nonhuman primate model.

Authors:  Richard J Noel; Vanessa Rivera-Amill; Shilpa Buch; Anil Kumar
Journal:  J Neurovirol       Date:  2008-08       Impact factor: 2.643

10.  Morphine promotes simian acquired immunodeficiency syndrome virus replication in monkey peripheral mononuclear cells: induction of CC chemokine receptor 5 expression for virus entry.

Authors:  Shunji Suzuki; Ann J Chuang; Linda F Chuang; Roy H Doi; Ronald Y Chuang
Journal:  J Infect Dis       Date:  2002-05-22       Impact factor: 5.226
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  3 in total

1.  Identification and molecular characterization of SIV Vpr R50G mutation associated with long term survival in SIV-infected morphine dependent and control macaques.

Authors:  Ivelisse Rivera; Yashira García; Mohitkumar R Gangwani; Richard J Noel; Lucianette Maldonado; Anil Kumar; Vanessa Rivera-Amill
Journal:  Virology       Date:  2013-08-28       Impact factor: 3.616

2.  Translational research in NeuroAIDS: a neuroimmune pharmacology-related course.

Authors:  Amanda Brown; Bruce Shiramizu; Avindra Nath; Valerie Wojna
Journal:  J Neuroimmune Pharmacol       Date:  2010-05-25       Impact factor: 4.147

Review 3.  Morphine and rapid disease progression in nonhuman primate model of AIDS: inverse correlation between disease progression and virus evolution.

Authors:  Vanessa Rivera-Amill; Peter S Silverstein; Richard J Noel; Santosh Kumar; Anil Kumar
Journal:  J Neuroimmune Pharmacol       Date:  2009-12-16       Impact factor: 4.147
  3 in total

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