Literature DB >> 19396640

Soft tissue sarcomas with non-EWS translocations: molecular genetic features and pathologic and clinical correlations.

Cyril Fisher1.   

Abstract

Many soft tissue sarcoma subtypes have consistent chromosomal translocations with novel fusion genes, which result in disordered cellular function. The microscopic appearances, immunophenotype and behaviour of such tumours relate to the genetic events to a variable extent. This paper reviews the molecular pathology and related morphological and clinical features of sarcomas with non-EWS translocations. These include synovial sarcoma, alveolar rhabdomyosarcoma, alveolar soft part sarcoma, dermatofibrosarcoma protuberans, low-grade fibromyxoid sarcoma, infantile fibrosarcoma and inflammatory myofibroblastic tumour.

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Year:  2009        PMID: 19396640     DOI: 10.1007/s00428-009-0776-0

Source DB:  PubMed          Journal:  Virchows Arch        ISSN: 0945-6317            Impact factor:   4.064


  193 in total

1.  Absence of SYT-SSX fusion products in soft tissue tumors other than synovial sarcoma.

Authors:  M van de Rijn; F G Barr; M H Collins; Q B Xiong; C Fisher
Journal:  Am J Clin Pathol       Date:  1999-07       Impact factor: 2.493

2.  The SYT protein involved in the t(X;18) synovial sarcoma translocation is a transcriptional activator localised in nuclear bodies.

Authors:  D Brett; S Whitehouse; P Antonson; J Shipley; C Cooper; G Goodwin
Journal:  Hum Mol Genet       Date:  1997-09       Impact factor: 6.150

3.  The precrystalline cytoplasmic granules of alveolar soft part sarcoma contain monocarboxylate transporter 1 and CD147.

Authors:  Marc Ladanyi; Cristina R Antonescu; Marija Drobnjak; Ann Baren; Man Yee Lui; David W Golde; Carlos Cordon-Cardo
Journal:  Am J Pathol       Date:  2002-04       Impact factor: 4.307

4.  Calretinin and other mesothelioma markers in synovial sarcoma: analysis of antigenic similarities and differences with malignant mesothelioma.

Authors:  M Miettinen; J Limon; A Niezabitowski; J Lasota
Journal:  Am J Surg Pathol       Date:  2001-05       Impact factor: 6.394

5.  Imatinib mesylate in a patient with metastatic disease originating from a dermatofibrosarcoma protuberans of the scalp.

Authors:  Bernd Kasper; Dominique Lossignol; Thierry Gil; Patrick Flamen; Nicolas De Saint Aubain; Ahmad Awada
Journal:  Anticancer Drugs       Date:  2006-11       Impact factor: 2.248

6.  Apo D in soft tissue tumors: a novel marker for dermatofibrosarcoma protuberans.

Authors:  Robert B West; Jeff Harvell; Sabine C Linn; Chih Long Liu; Wijan Prapong; Tina Hernandez-Boussard; Kelli Montgomery; Torsten O Nielsen; Brian P Rubin; Rajiv Patel; John R Goldblum; Patrick O Brown; Matt van de Rijn; Chih Long Lui
Journal:  Am J Surg Pathol       Date:  2004-08       Impact factor: 6.394

7.  A highly conserved NTRK3 C-terminal sequence in the ETV6-NTRK3 oncoprotein binds the phosphotyrosine binding domain of insulin receptor substrate-1: an essential interaction for transformation.

Authors:  Chris L Lannon; Matthew J Martin; Cristina E Tognon; Wook Jin; Seong-Jin Kim; Poul H B Sorensen
Journal:  J Biol Chem       Date:  2003-12-09       Impact factor: 5.157

8.  Giant cell fibroblastoma transforming into dermatofibrosarcoma protuberans.

Authors:  P W Allen; J Zwi
Journal:  Am J Surg Pathol       Date:  1992-11       Impact factor: 6.394

9.  A novel variant of SYT-SSX1 fusion gene in a case of spindle cell synovial sarcoma.

Authors:  Lenka Krsková; David Sumerauer; Eva Stejskalová; Roman Kodet
Journal:  Diagn Mol Pathol       Date:  2007-09

10.  Dermatofibrosarcoma protuberans, giant cell fibroblastoma, and hybrid lesions in children: clinicopathologic comparative analysis of 28 cases with molecular data--a study from the French Federation of Cancer Centers Sarcoma Group.

Authors:  Marie-Josée Terrier-Lacombe; Louis Guillou; Georges Maire; Philippe Terrier; Dominique Ranchère Vince; Nicolas de Saint Aubain Somerhausen; Françoise Collin; Florence Pedeutour; Jean-Michel Coindre
Journal:  Am J Surg Pathol       Date:  2003-01       Impact factor: 6.394

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  7 in total

1.  The many faces of atypical Ewing's sarcoma. A true entity mimicking sarcomas, carcinomas and lymphomas.

Authors:  Isidro Machado; Rosa Noguera; Eduardo Alcaraz Mateos; Silvia Calabuig-Fariñas; F Ignacio Aranda López; Antonio Martínez; Samuel Navarro; Antonio Llombart-Bosch
Journal:  Virchows Arch       Date:  2010-12-23       Impact factor: 4.064

2.  Imatinib and Dasatinib Inhibit Hemangiosarcoma and Implicate PDGFR-β and Src in Tumor Growth.

Authors:  Erin B Dickerson; Kevin Marley; Wade Edris; Jeffrey W Tyner; Vidya Schalk; Valerie Macdonald; Marc Loriaux; Brian J Druker; Stuart C Helfand
Journal:  Transl Oncol       Date:  2013-04-01       Impact factor: 4.243

Review 3.  New therapeutic targets in soft tissue sarcoma.

Authors:  Elizabeth G Demicco; Robert G Maki; Dina C Lev; Alexander J Lazar
Journal:  Adv Anat Pathol       Date:  2012-05       Impact factor: 3.875

4.  The comparative utility of fluorescence in situ hybridization and reverse transcription-polymerase chain reaction in the diagnosis of alveolar rhabdomyosarcoma.

Authors:  Khin Thway; Jayson Wang; Dorte Wren; Melissa Dainton; David Gonzalez; John Swansbury; Cyril Fisher
Journal:  Virchows Arch       Date:  2015-04-26       Impact factor: 4.064

5.  Curent concepts in pathology of soft tissue sarcoma.

Authors:  Nuzhat Husain; Nidhi Verma
Journal:  Indian J Surg Oncol       Date:  2012-04-03

6.  Gastrointestinal Mesenchymal Neoplasms other than Gastrointestinal Stromal Tumors: Focusing on Their Molecular Aspects.

Authors:  Thomas P Plesec
Journal:  Patholog Res Int       Date:  2011-02-16

7.  Inflammatory myofibroblastic tumour arising in the adrenal gland: a case report.

Authors:  My-Anh Tran-Dang; Neal Banga; Bernard Khoo; Alan W H Bates
Journal:  J Med Case Rep       Date:  2014-12-07
  7 in total

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