Literature DB >> 19396442

[Virilizing adrenal ganglioneuroma : A rare differential diagnosis in testosterone secreting adrenal tumours].

N T Gaisa1, G Klöppel, B Brehmer, J Neulen, P Stephan, R Knüchel, A Donner.   

Abstract

Testosterone secreting tumours of the adrenal glands are usually adrenal carcinomas or adenomas. Here we report the rare case of an adrenal ganglioneuroma with ectopic Leydig cells, a so-called virilizing adrenal ganglioneuroma. Clinically it is characterized by symptoms of virilization, histologically by the occurrence of a population of eosinophilic cells. In the absence of crystalloids of Reinke this cell population can be identified as Leydig cells based on positive immunohistochemical staining of inhibin and calretinin.

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Year:  2009        PMID: 19396442     DOI: 10.1007/s00292-009-1145-0

Source DB:  PubMed          Journal:  Pathologe        ISSN: 0172-8113            Impact factor:   1.011


  8 in total

1.  Ganglioneuroma of adrenal medulla containing cells morphologically identical to hilus cells (extraparenchymal Leydig cells).

Authors:  R E SCULLY; R B COHEN
Journal:  Cancer       Date:  1961 Mar-Apr       Impact factor: 6.860

2.  Virilizing adrenal ganglioneuroma containing Leydig cells.

Authors:  G Godlewski; A H Nguyen Trong; J Tang; R Semler-Collery; J M Joujoux; A F Gaujoux
Journal:  Acta Chir Belg       Date:  1993 Jul-Aug       Impact factor: 1.090

3.  Virilizing adrenal ganglioneuroma.

Authors:  E Mack; G E Sarto; A B Crummy; I H Carlson; L B Curet; J Wu
Journal:  JAMA       Date:  1978-05-26       Impact factor: 56.272

Review 4.  [Tumors of the adrenal medulla and the paraganglia].

Authors:  G Klöppel
Journal:  Pathologe       Date:  2003-05-29       Impact factor: 1.011

5.  Inhibin A is a sensitive and specific marker for testicular sex cord-stromal tumors.

Authors:  K A Iczkowski; D G Bostwick; P C Roche; J C Cheville
Journal:  Mod Pathol       Date:  1998-08       Impact factor: 7.842

6.  Ectopic Leydig cells of testis An immunohistochemical study on tissue microarray.

Authors:  Sun-Young Jun; Jae Y Ro; Yong W Park; Kyu-Rae Kim; Alberto G Ayala
Journal:  Ann Diagn Pathol       Date:  2007-10-24       Impact factor: 2.090

7.  Testosterone-secreting adrenal ganglioneuroma containing Leydig cells.

Authors:  P Aguirre; R E Scully
Journal:  Am J Surg Pathol       Date:  1983-10       Impact factor: 6.394

8.  Calretinin: a valuable marker of normal and neoplastic Leydig cells of the testis.

Authors:  David Augusto; Emmanuelle Leteurtre; Alexandre De La Taille; Bernard Gosselin; Xavier Leroy
Journal:  Appl Immunohistochem Mol Morphol       Date:  2002-06
  8 in total
  2 in total

Review 1.  Adrenal ganglioneuroma: What you need to know.

Authors:  Konstantinos S Mylonas; Dimitrios Schizas; Konstantinos P Economopoulos
Journal:  World J Clin Cases       Date:  2017-10-16       Impact factor: 1.337

2.  Adrenal Ganglioneuroma: A Case Report.

Authors:  Hayat Aynaou; Houda Salhi; Hanan El Ouahabi
Journal:  Cureus       Date:  2022-08-03
  2 in total

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