Literature DB >> 19395911

Complete and durable response of choroid metastasis from non-small cell lung cancer with systemic bevacizumab and chemotherapy.

Ben George1, William J Wirostko, Thomas B Connor, Nicholas W Choong.   

Abstract

Ocular metastasis from lung cancer is uncommon. We report a patient with metastatic non-small cell lung cancer who was found to have a metastatic lesion in the choroid at the time of presentation. The patient was treated with carboplatin, gemcitabine, and bevacizumab. After three cycles of chemotherapy, radiologic imaging and ophthalmologic examination demonstrated complete resolution of the choroid lesion. This case report demonstrates the durable response of choroidal metastasis from non-small cell lung cancer to systemic bevacizumab and chemotherapy.

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Year:  2009        PMID: 19395911     DOI: 10.1097/JTO.0b013e31819c9a73

Source DB:  PubMed          Journal:  J Thorac Oncol        ISSN: 1556-0864            Impact factor:   15.609


  22 in total

1.  Unilateral temporal haemianopia in a patient with non-small cell lung cancer: intraocular metastasis despite chemotherapy.

Authors:  Alexander Liu; Harman Saman; Pawan Pusalkar
Journal:  BMJ Case Rep       Date:  2011-07-28

2.  Comment on 'Failure of intravitreal bevacizumab in the treatment of choroidal metastasis'.

Authors:  H R Kourie; J Antoun; J Kattan
Journal:  Eye (Lond)       Date:  2015-09-18       Impact factor: 3.775

3.  Intravitreal bevacizumab in the successful management of choroidal metastases secondary to lung and breast cancer unresponsive to systemic therapy: a case series.

Authors:  V Fenicia; S Abdolrahimzadeh; G Mannino; S Verrilli; M Balestrieri; S M Recupero
Journal:  Eye (Lond)       Date:  2014-04-25       Impact factor: 3.775

4.  Development of a new choroidal metastasis in resistance to crizotinib therapy in anaplastic lymphoma kinase-rearranged non-small cell lung cancer.

Authors:  Zhi-Hua Cui; Yan Zhang; Ling-Ling Liang; Zhao-Hui Li; Inna Abramova; Qian Hao
Journal:  Int J Ophthalmol       Date:  2017-02-18       Impact factor: 1.779

Review 5.  Emerging treatments for choroidal metastases.

Authors:  Connie J Chen; Allison N McCoy; Julie Brahmer; James T Handa
Journal:  Surv Ophthalmol       Date:  2011 Nov-Dec       Impact factor: 6.048

6.  Intravitreal bevacizumab for consecutive multiple choroidal breast metastatic lesions.

Authors:  Ahmad M Mansour; Ramzi Alameddine
Journal:  BMJ Case Rep       Date:  2012-06-14

7.  Choroidal Metastasis as Initial Presentation in Adenocarcinoma of Lung: A Case Report.

Authors:  Saroj Kumar Das; Tapan Kumar Sahoo; Sucheta Parija; Saroj Kumar Das Majumdar; Dillip Kumar Parida
Journal:  J Clin Diagn Res       Date:  2017-03-01

8.  A case series of NSCLC patients with different molecular characteristics and choroidal metastases: improvement in vision with treatment including pemetrexed and bevacizumab.

Authors:  Jonathan W Riess; Seema Nagpal; Millie Das; Joel W Neal; Jonathan W Kim; Heather A Wakelee
Journal:  J Thorac Oncol       Date:  2013-02       Impact factor: 15.609

9.  Treatment of choroid metastasis from lung adenocarcinoma with bevacizumab-containing chemotherapy: A case report.

Authors:  Kenichi Makabe; Koichi Kurishima; Toshihiro Shiozawa; Kunihiko Miyazaki; Gen Ohara; Katsunori Kagohashi; Hiroaki Satoh; Nobuyuki Hizawa
Journal:  Exp Ther Med       Date:  2015-11-25       Impact factor: 2.447

10.  Blurred vision due to choroidal metastasis as the first manifestation of lung cancer: a case report.

Authors:  Christos Asteriou; Dimitrios Konstantinou; Athanassios Kleontas; Dimitrios Paliouras; Georgios Samanidis; Fani Papadopoulou; Nikolaos Barbetakis
Journal:  World J Surg Oncol       Date:  2010-01-08       Impact factor: 2.754

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