Literature DB >> 19394824

Total synthesis and determination of the absolute configuration of FD-838, a naturally occurring azaspirobicyclic product.

Yujiro Hayashi1, Kuppusamy Sankar, Hayato Ishikawa, Yuriko Nozawa, Kazutoshi Mizoue, Hideaki Kakeya.   

Abstract

The first asymmetric total synthesis of FD-838, a naturally occurring azaspirobicyclic product, has been accomplished allowing determination of its absolute stereochemistry.

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Year:  2009        PMID: 19394824     DOI: 10.1016/j.bmcl.2009.03.154

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  3 in total

1.  A photoisomerization-coupled asymmetric Stetter reaction: application to the total synthesis of three diastereomers of (-)-cephalimysin A.

Authors:  Stephen P Lathrop; Tomislav Rovis
Journal:  Chem Sci       Date:  2013-04       Impact factor: 9.825

2.  Catalytic asymmetric synthesis of 3,2'-pyrrolinyl spirooxindoles via conjugate addition/Schmidt-type rearrangement of vinyl azides and (E)-alkenyloxindoles.

Authors:  Ziwei Zhong; Zhijie Xiao; Xiaohua Liu; Weidi Cao; Xiaoming Feng
Journal:  Chem Sci       Date:  2020-09-28       Impact factor: 9.825

3.  Assignment of the CD Cotton Effect to the Chiral Center in Pseurotins, and the Stereochemical Revision of Pseurotin A₂.

Authors:  Takeshi Yamada; Mina Ohshima; Kaori Yuasa; Takashi Kikuchi; Reiko Tanaka
Journal:  Mar Drugs       Date:  2016-04-09       Impact factor: 5.118

  3 in total

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