Literature DB >> 19394161

The lateral decubitus breast boost: description, rationale, and efficacy.

Michelle S Ludwig1, Marsha D McNeese, Thomas A Buchholz, George H Perkins, Eric A Strom.   

Abstract

PURPOSE: To describe and evaluate the modified lateral decubitus boost, a breast irradiation technique. Patients are repositioned and resimulated for electron boost to minimize the necessary depth for the electron beam and optimize target volume coverage. METHODS AND MATERIALS: A total of 2,606 patients were treated with post-lumpectomy radiation at our institution between January 1, 2000, and February 1, 2008. Of these, 231 patients underwent resimulation in the lateral decubitus position with electron boost. Distance from skin to the maximal depth of target volume was measured in both the original and boost plans. Age, body mass index (BMI), boost electron energy, and skin reaction were evaluated.
RESULTS: Resimulation in the lateral decubitus position reduced the distance from skin to maximal target volume depth in all patients. Average depth reduction by repositioning was 2.12 cm, allowing for an average electron energy reduction of approximately 7 MeV. Mean skin entrance dose was reduced from about 90% to about 85% (p < 0.001). Only 14 patients (6%) experienced moist desquamation in the boost field at the end of treatment. Average BMI of these patients was 30.4 (range, 17.8-50.7). BMI greater than 30 was associated with more depth reduction by repositioning and increased risk of moist desquamation.
CONCLUSIONS: The lateral decubitus position allows for a decrease in the distance from the skin to the target volume depth, improving electron coverage of the tumor bed while reducing skin entrance dose. This is a well-tolerated regimen for a patient population with a high BMI or deep tumor location.

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Year:  2010        PMID: 19394161     DOI: 10.1016/j.ijrobp.2009.01.053

Source DB:  PubMed          Journal:  Int J Radiat Oncol Biol Phys        ISSN: 0360-3016            Impact factor:   7.038


  5 in total

Review 1.  The two major epidemics of the twenty-first century: obesity and cancer.

Authors:  Orit Kaidar-Person; Gil Bar-Sela; Benjamin Person
Journal:  Obes Surg       Date:  2011-11       Impact factor: 4.129

2.  Unintended cardiac irradiation during left-sided breast cancer radiotherapy.

Authors:  R B Goody; J O'Hare; K McKenna; L Dearey; J Robinson; P Bell; J Clarke; J J A McAleer; J M O'Sullivan; G G Hanna
Journal:  Br J Radiol       Date:  2013-02       Impact factor: 3.039

3.  Cardiac risk and MCNP/SISCODES doses in RT of the left internal mammary chain with photon and electron portals.

Authors:  Tarcisio Passos Ribeiro de Campos; Bruno M Mendes; Bruno Trindade; Wagner L Araujo
Journal:  Rep Pract Oncol Radiother       Date:  2018-08-13

Review 4.  Post-lumpectomy radiation therapy boost in breast cancer patients: evidence revisited.

Authors:  Majd Kayali; Joseph Abi Jaoude; Paul Ramia; Hazem Assi; Fady Geara; Philip Poortmans; Youssef H Zeidan
Journal:  Ecancermedicalscience       Date:  2021-03-01

5.  Is there an advantage to delivering breast boost in the lateral decubitus position?

Authors:  Neeta Kannan; Peyman Kabolizadeh; Hayeon Kim; Christopher Houser; Sushil Beriwal
Journal:  Radiat Oncol       Date:  2012-09-24       Impact factor: 3.481

  5 in total

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