Literature DB >> 19394136

Delayed coma in head injury: consider cerebral fat embolism.

Zwany Metting1, Lars A Rödiger, Joost G Regtien, Joukje van der Naalt.   

Abstract

OBJECTIVE: To describe a case of a young man with delayed coma after mild head injury, suggestive of cerebral fat embolism (CFE). To underline the value of MR imaging in the differential diagnosis of secondary deterioration in mild head injury. CASE REPORT: A 21-year-old man admitted with mild head injury after a fall with facial fractures and long bone fractures. He was admitted to the intensive care unit and was mechanically ventilated. Weaning was not possible because of desaturations and pulmonary congestion. Low platelet count and anaemia developed. On several time points during his admission cerebral imaging data were obtained. Non-contrast CT on admission was normal while follow-up MRI showed extensive white matter abnormalities. These imaging abnormalities combined with the clinical presentation suggests cerebral fat embolism (CFE) as the most likely cause of secondary deterioration in our patient.
CONCLUSIONS: In head injured patients with long bone fractures one should consider cerebral fat embolism. When the classical clinical syndrome is not present, MR imaging is warranted for diagnosis and to exclude other causes of secondary deterioration.

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Year:  2009        PMID: 19394136     DOI: 10.1016/j.clineuro.2009.03.005

Source DB:  PubMed          Journal:  Clin Neurol Neurosurg        ISSN: 0303-8467            Impact factor:   1.876


  6 in total

Review 1.  Dynamic MR imaging patterns of cerebral fat embolism: a systematic review with illustrative cases.

Authors:  K-H Kuo; Y-J Pan; Y-J Lai; W-K Cheung; F-C Chang; J Jarosz
Journal:  AJNR Am J Neuroradiol       Date:  2013-05-02       Impact factor: 3.825

2.  Clinical and radiographic improvement following cerebral fat emboli.

Authors:  Anand I Rughani; Jeffrey E Florman; David B Seder
Journal:  Neurocrit Care       Date:  2011-08       Impact factor: 3.210

Review 3.  Pathophysiology, clinics and diagnostics of non-thrombotic pulmonary embolism.

Authors:  Martina Montagnana; Gianfranco Cervellin; Massimo Franchini; Giuseppe Lippi
Journal:  J Thromb Thrombolysis       Date:  2011-05       Impact factor: 2.300

4.  Late recovery in cerebral fat embolism.

Authors:  Kp Srikanth; Sr Sundararajan; S Rajasekaran
Journal:  Indian J Orthop       Date:  2014-01       Impact factor: 1.251

5.  Massive cerebral fat embolism leading to brain death: A rare presentation.

Authors:  Richa Aggarwal; Sugata Pal; Kapil Dev Soni; Shivanand Gamangatti
Journal:  Indian J Crit Care Med       Date:  2015-11

6.  Cerebral and pulmonary fat embolism after unilateral total knee arthroplasty.

Authors:  David Figueroa; Francisco Figueroa; Rafael Calvo Mena; María Figueroa
Journal:  Arthroplast Today       Date:  2019-10-31
  6 in total

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