Literature DB >> 19392526

Particle segregation and dynamics in confined flows.

Dino Di Carlo1, Jon F Edd, Katherine J Humphry, Howard A Stone, Mehmet Toner.   

Abstract

Nonlinearity in finite-Reynolds-number flow results in particle migration transverse to fluid streamlines, producing the well-known "tubular pinch effect" in cylindrical pipes. Here we investigate these nonlinear effects in highly confined systems where the particle size approaches the channel dimensions. Experimental and numerical results reveal distinctive dynamics, including complex scaling of lift forces with channel and particle geometry. The unique behavior described in this Letter has broad implications for confined particulate flows.

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Year:  2009        PMID: 19392526      PMCID: PMC4485430          DOI: 10.1103/PhysRevLett.102.094503

Source DB:  PubMed          Journal:  Phys Rev Lett        ISSN: 0031-9007            Impact factor:   9.161


  5 in total

1.  Pinched flow fractionation: continuous size separation of particles utilizing a laminar flow profile in a pinched microchannel.

Authors:  Masumi Yamada; Megumi Nakashima; Minoru Seki
Journal:  Anal Chem       Date:  2004-09-15       Impact factor: 6.986

2.  Continuous inertial focusing, ordering, and separation of particles in microchannels.

Authors:  Dino Di Carlo; Daniel Irimia; Ronald G Tompkins; Mehmet Toner
Journal:  Proc Natl Acad Sci U S A       Date:  2007-11-19       Impact factor: 11.205

3.  Equilibrium separation and filtration of particles using differential inertial focusing.

Authors:  Dino Di Carlo; Jon F Edd; Daniel Irimia; Ronald G Tompkins; Mehmet Toner
Journal:  Anal Chem       Date:  2008-02-15       Impact factor: 6.986

4.  Controlled encapsulation of single-cells into monodisperse picolitre drops.

Authors:  Jon F Edd; Dino Di Carlo; Katherine J Humphry; Sarah Köster; Daniel Irimia; David A Weitz; Mehmet Toner
Journal:  Lab Chip       Date:  2008-06-13       Impact factor: 6.799

Review 5.  Field-flow fractionation: analysis of macromolecular, colloidal, and particulate materials.

Authors:  J C Giddings
Journal:  Science       Date:  1993-06-04       Impact factor: 47.728

  5 in total
  74 in total

1.  Inertial focusing dynamics in spiral microchannels.

Authors:  Joseph M Martel; Mehmet Toner
Journal:  Phys Fluids (1994)       Date:  2012-03-06       Impact factor: 3.521

2.  High throughput single-cell and multiple-cell micro-encapsulation.

Authors:  Todd P Lagus; Jon F Edd
Journal:  J Vis Exp       Date:  2012-06-15       Impact factor: 1.355

3.  Intrinsic particle-induced lateral transport in microchannels.

Authors:  Hamed Amini; Elodie Sollier; Westbrook M Weaver; Dino Di Carlo
Journal:  Proc Natl Acad Sci U S A       Date:  2012-07-03       Impact factor: 11.205

4.  Particle focusing in staged inertial microfluidic devices for flow cytometry.

Authors:  John Oakey; Robert W Applegate; Erik Arellano; Dino Di Carlo; Steven W Graves; Mehmet Toner
Journal:  Anal Chem       Date:  2010-05-01       Impact factor: 6.986

5.  Dynamic self-assembly and control of microfluidic particle crystals.

Authors:  Wonhee Lee; Hamed Amini; Howard A Stone; Dino Di Carlo
Journal:  Proc Natl Acad Sci U S A       Date:  2010-12-13       Impact factor: 11.205

6.  Dean-flow-coupled elasto-inertial three-dimensional particle focusing under viscoelastic flow in a straight channel with asymmetrical expansion-contraction cavity arrays.

Authors:  D Yuan; J Zhang; S Yan; C Pan; G Alici; N T Nguyen; W H Li
Journal:  Biomicrofluidics       Date:  2015-07-29       Impact factor: 2.800

7.  Simulation and experimental determination of the online separation of blood components with the help of microfluidic cascading spirals.

Authors:  Lisa Sprenger; Silvio Dutz; Thomas Schneider; Stefan Odenbach; Urs O Häfeli
Journal:  Biomicrofluidics       Date:  2015-07-29       Impact factor: 2.800

8.  Size-based hydrodynamic rare tumor cell separation in curved microfluidic channels.

Authors:  Jiashu Sun; Chao Liu; Mengmeng Li; Jidong Wang; Yunlei Xianyu; Guoqing Hu; Xingyu Jiang
Journal:  Biomicrofluidics       Date:  2013-01-07       Impact factor: 2.800

9.  Optimal control of particle separation in inertial microfluidics.

Authors:  Christopher Prohm; Fredi Tröltzsch; Holger Stark
Journal:  Eur Phys J E Soft Matter       Date:  2013-10-25       Impact factor: 1.890

10.  Inertio-elastic focusing of bioparticles in microchannels at high throughput.

Authors:  Eugene J Lim; Thomas J Ober; Jon F Edd; Salil P Desai; Douglas Neal; Ki Wan Bong; Patrick S Doyle; Gareth H McKinley; Mehmet Toner
Journal:  Nat Commun       Date:  2014-06-18       Impact factor: 14.919

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