| Literature DB >> 1939201 |
C T Samudzi1, L E Burton, J R Rubin.
Abstract
The crystal structure of recombinant rabbit interferon-gamma was solved by the multiple isomorphous replacement technique at 2.7-A resolution and refined to a crystallographic R-factor of 26.2%. The interferon crystallizes with one-half of the functional dimer in the asymmetric unit, with the two polypeptide chains of the dimer related by a crystallographic 2-fold symmetry axis. The structure is predominantly alpha-helical with extensive interdigitation of the alpha-helical segments of the two polypeptide chains.Entities:
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Year: 1991 PMID： 1939201
Source DB: PubMed Journal: J Biol Chem ISSN： 0021-9258 Impact factor: 5.157