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Literature DB >> 19390548

Chemotherapy: The role of ifosfamide and etoposide in Ewing sarcoma.

Abstract

The EICESS-92 Trial compared the efficacy of cyclophosphamide and ifosfamide in patients with Ewing sarcoma. Subgroup analysis suggested that patients with large, localized tumors benefited from the addition of etoposide, whereas patients with metastases did not.

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Year: 2009 PMID： 19390548 DOI： 10.1038/nrclinonc.2009.25

Source DB: PubMed Journal: Nat Rev Clin Oncol ISSN： 1759-4774 Impact factor: 66.675

7 in total

1. Localized Ewing tumor of bone: final results of the cooperative Ewing's Sarcoma Study CESS 86.

Authors: M Paulussen; S Ahrens; J Dunst; W Winkelmann; G U Exner; R Kotz; G Amann; B Dockhorn-Dworniczak; D Harms; S Müller-Weihrich; K Welte; B Kornhuber; G Janka-Schaub; U Göbel; J Treuner; P A Voûte; A Zoubek; H Gadner; H Jürgens
Journal: J Clin Oncol Date: 2001-03-15 Impact factor: 44.544

2. Results of the EICESS-92 Study: two randomized trials of Ewing's sarcoma treatment--cyclophosphamide compared with ifosfamide in standard-risk patients and assessment of benefit of etoposide added to standard treatment in high-risk patients.

Authors: Michael Paulussen; Alan W Craft; Ian Lewis; Allan Hackshaw; Carolyn Douglas; Jürgen Dunst; Andreas Schuck; Winfried Winkelmann; Gabriele Köhler; Christopher Poremba; Andreas Zoubek; Ruth Ladenstein; Henk van den Berg; Andrea Hunold; Anna Cassoni; David Spooner; Robert Grimer; Jeremy Whelan; Anne McTiernan; Herbert Jürgens
Journal: J Clin Oncol Date: 2008-09-20 Impact factor: 44.544

3. Ifosfamide with mesna uroprotection and etoposide: an effective regimen in the treatment of recurrent sarcomas and other tumors of children and young adults.

Authors: J S Miser; T J Kinsella; T J Triche; M Tsokos; P Jarosinski; R Forquer; R Wesley; I Magrath
Journal: J Clin Oncol Date: 1987-08 Impact factor: 44.544

4. Addition of ifosfamide and etoposide to standard chemotherapy for Ewing's sarcoma and primitive neuroectodermal tumor of bone.

Authors: Holcombe E Grier; Mark D Krailo; Nancy J Tarbell; Michael P Link; Christopher J H Fryer; Douglas J Pritchard; Mark C Gebhardt; Paul S Dickman; Elizabeth J Perlman; Paul A Meyers; Sarah S Donaldson; Sheila Moore; Aaron R Rausen; Teresa J Vietti; James S Miser
Journal: N Engl J Med Date: 2003-02-20 Impact factor: 91.245

5. A phase II study of ifosfamide in the treatment of recurrent sarcomas in young people.

Authors: I Magrath; J Sandlund; A Raynor; S Rosenberg; V Arasi; J Miser
Journal: Cancer Chemother Pharmacol Date: 1986 Impact factor: 3.333

6. No benefit of ifosfamide in Ewing's sarcoma: a nonrandomized study of the French Society of Pediatric Oncology.

Authors: O Oberlin; J L Habrand; J M Zucker; M Brunat-Mentigny; M J Terrier-Lacombe; J Dubousset; J C Gentet; C Schmitt; D Ponvert; C Carrié
Journal: J Clin Oncol Date: 1992-09 Impact factor: 44.544

7. Ifosfamide-containing chemotherapy in Ewing's sarcoma: The Second United Kingdom Children's Cancer Study Group and the Medical Research Council Ewing's Tumor Study.

Authors: A Craft; S Cotterill; A Malcolm; D Spooner; R Grimer; R Souhami; J Imeson; I Lewis
Journal: J Clin Oncol Date: 1998-11 Impact factor: 44.544

7 in total

4 in total

Chemotherapy: The role of ifosfamide and etoposide in Ewing sarcoma.

1. Localized Ewing tumor of bone: final results of the cooperative Ewing's Sarcoma Study CESS 86.

2. Results of the EICESS-92 Study: two randomized trials of Ewing's sarcoma treatment--cyclophosphamide compared with ifosfamide in standard-risk patients and assessment of benefit of etoposide added to standard treatment in high-risk patients.

3. Ifosfamide with mesna uroprotection and etoposide: an effective regimen in the treatment of recurrent sarcomas and other tumors of children and young adults.

4. Addition of ifosfamide and etoposide to standard chemotherapy for Ewing's sarcoma and primitive neuroectodermal tumor of bone.

5. A phase II study of ifosfamide in the treatment of recurrent sarcomas in young people.

6. No benefit of ifosfamide in Ewing's sarcoma: a nonrandomized study of the French Society of Pediatric Oncology.

7. Ifosfamide-containing chemotherapy in Ewing's sarcoma: The Second United Kingdom Children's Cancer Study Group and the Medical Research Council Ewing's Tumor Study.

Review 1. Extraosseous Ewing Sarcoma: Diagnosis, Prognosis and Optimal Management.

2. Pathobiologic markers of the ewing sarcoma family of tumors: state of the art and prediction of behaviour.

3. In search of targeted therapies for childhood cancer.

Review 4. Combinatorial strategies for the induction of immunogenic cell death.