| Literature DB >> 19390050 |
Richard A Gibbs, Jeremy F Taylor, Curtis P Van Tassell, William Barendse, Kellye A Eversole, Clare A Gill, Ronnie D Green, Debora L Hamernik, Steven M Kappes, Sigbjørn Lien, Lakshmi K Matukumalli, John C McEwan, Lynne V Nazareth, Robert D Schnabel, George M Weinstock, David A Wheeler, Paolo Ajmone-Marsan, Paul J Boettcher, Alexandre R Caetano, Jose Fernando Garcia, Olivier Hanotte, Paola Mariani, Loren C Skow, Tad S Sonstegard, John L Williams, Boubacar Diallo, Lemecha Hailemariam, Mario L Martinez, Chris A Morris, Luiz O C Silva, Richard J Spelman, Woudyalew Mulatu, Keyan Zhao, Colette A Abbey, Morris Agaba, Flábio R Araujo, Rowan J Bunch, James Burton, Chiara Gorni, Hanotte Olivier, Blair E Harrison, Bill Luff, Marco A Machado, Joel Mwakaya, Graham Plastow, Warren Sim, Timothy Smith, Merle B Thomas, Alessio Valentini, Paul Williams, James Womack, John A Woolliams, Yue Liu, Xiang Qin, Kim C Worley, Chuan Gao, Huaiyang Jiang, Stephen S Moore, Yanru Ren, Xing-Zhi Song, Carlos D Bustamante, Ryan D Hernandez, Donna M Muzny, Shobha Patil, Anthony San Lucas, Qing Fu, Matthew P Kent, Richard Vega, Aruna Matukumalli, Sean McWilliam, Gert Sclep, Katarzyna Bryc, Jungwoo Choi, Hong Gao, John J Grefenstette, Brenda Murdoch, Alessandra Stella, Rafael Villa-Angulo, Mark Wright, Jan Aerts, Oliver Jann, Riccardo Negrini, Mike E Goddard, Ben J Hayes, Daniel G Bradley, Marcos Barbosa da Silva, Lilian P L Lau, George E Liu, David J Lynn, Francesca Panzitta, Ken G Dodds.
Abstract
The imprints of domestication and breed development on the genomes of livestock likely differ from those of companion animals. A deep draft sequence assembly of shotgun reads from a single Hereford female and comparative sequences sampled from six additional breeds were used to develop probes to interrogate 37,470 single-nucleotide polymorphisms (SNPs) in 497 cattle from 19 geographically and biologically diverse breeds. These data show that cattle have undergone a rapid recent decrease in effective population size from a very large ancestral population, possibly due to bottlenecks associated with domestication, selection, and breed formation. Domestication and artificial selection appear to have left detectable signatures of selection within the cattle genome, yet the current levels of diversity within breeds are at least as great as exists within humans.Entities:
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Year: 2009 PMID： 19390050 PMCID： PMC2735092 DOI： 10.1126/science.1167936
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728