Literature DB >> 1938931

Differential response of the bvg virulence regulon of Bordetella pertussis to MgSO4 modulation.

V Scarlato1, R Rappuoli.   

Abstract

Magnesium sulfate is known to repress the expression of the virulence factors of Bordetella pertussis that are coordinately regulated by the bvg locus. We have tested the time required by MgSO4 to repress the synthesis of several bvg-regulated mRNA species and found that the promoters of the virulence genes (pertussis toxin, adenylate cyclase, and filamentous hemagglutinin) are repressed in 6 min, while the autogenously regulated promoters of the bvg locus (P1, P3, and P4) are repressed only several hours later. These data show a differential behavior between regulated and autoregulated genes of the bvg regulon.

Entities:  

Mesh：

Substances：

Year:  1991        PMID： 1938931      PMCID： PMC209252          DOI： 10.1128/jb.173.22.7401-7404.1991

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  25 in total

1.  Identification of Bordetella pertussis regulatory sequences required for transcriptional activation of the fhaB gene and autoregulation of the bvgAS operon.

Authors:  C R Roy; S Falkow
Journal:  J Bacteriol       Date:  1991-04       Impact factor: 3.490

2.  Positive transcriptional feedback at the bvg locus controls expression of virulence factors in Bordetella pertussis.

Authors:  V Scarlato; A Prugnola; B Aricó; R Rappuoli
Journal:  Proc Natl Acad Sci U S A       Date:  1990-09       Impact factor: 11.205

3.  Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids.

Authors:  A J Berk; P A Sharp
Journal:  Cell       Date:  1977-11       Impact factor: 41.582

4.  Escherichia coli RNA polymerase-rifampicin complexes bound at promoter sites block RNA chain elongation by Escherichia coli RNA polymerase and T7-specific RNA polymerase.

Authors:  G A Kassavetis; K M Kaya; M J Chamberlin
Journal:  Biochemistry       Date:  1978-12-26       Impact factor: 3.162

5.  A simple chemically defined medium for the production of phase I Bordetella pertussis.

Authors:  D W Stainer; M J Scholte
Journal:  J Gen Microbiol       Date:  1970-10

6.  Pertussis toxin and extracytoplasmic adenylate cyclase as virulence factors of Bordetella pertussis.

Authors:  A A Weiss; E L Hewlett; G A Myers; S Falkow
Journal:  J Infect Dis       Date:  1984-08       Impact factor: 5.226

7.  Cloning and sequencing of the pertussis toxin genes: operon structure and gene duplication.

Authors:  A Nicosia; M Perugini; C Franzini; M C Casagli; M G Borri; G Antoni; M Almoni; P Neri; G Ratti; R Rappuoli
Journal:  Proc Natl Acad Sci U S A       Date:  1986-07       Impact factor: 11.205

8.  Rapidity of antigenic modulation of Bordetella pertussis in modified Hornibrook medium.

Authors:  E O Idigbe; R Parton; A C Wardlaw
Journal:  J Med Microbiol       Date:  1981-11       Impact factor: 2.472

9.  Tn5-induced mutations affecting virulence factors of Bordetella pertussis.

Authors:  A A Weiss; E L Hewlett; G A Myers; S Falkow
Journal:  Infect Immun       Date:  1983-10       Impact factor: 3.441

10.  Modulation of Bordetella pertussis by nicotinic acid.

Authors:  W L McPheat; A C Wardlaw; P Novotny
Journal:  Infect Immun       Date:  1983-08       Impact factor: 3.441
View more
  15 in total

1.  Genetic and biochemical analyses of BvgA interaction with the secondary binding region of the fha promoter of Bordetella pertussis.

Authors:  P E Boucher; M S Yang; D M Schmidt; S Stibitz
Journal:  J Bacteriol       Date:  2001-01       Impact factor: 3.490

2.  Modulation of adenylate cyclase toxin production as Bordetella pertussis enters human macrophages.

Authors:  H R Masure
Journal:  Proc Natl Acad Sci U S A       Date:  1992-07-15       Impact factor: 11.205

3.  Bordetella pertussis risA, but not risS, is required for maximal expression of Bvg-repressed genes.

Authors:  Trevor H Stenson; Andrew G Allen; Jehan A Al-Meer; Duncan Maskell; Mark S Peppler
Journal:  Infect Immun       Date:  2005-09       Impact factor: 3.441

4.  Mutations in the bvgA gene of Bordetella pertussis that differentially affect regulation of virulence determinants.

Authors:  S Stibitz
Journal:  J Bacteriol       Date:  1994-09       Impact factor: 3.490

5.  Evidence for phenotypic bistability resulting from transcriptional interference of bvgAS in Bordetella bronchiseptica.

Authors:  Eliza Mason; Michael W Henderson; Erich V Scheller; Matthew S Byrd; Peggy A Cotter
Journal:  Mol Microbiol       Date:  2013-09-30       Impact factor: 3.501

6.  The BvgAS signal transduction system regulates biofilm development in Bordetella.

Authors:  Meenu Mishra; Gina Parise; Kara D Jackson; Daniel J Wozniak; Rajendar Deora
Journal:  J Bacteriol       Date:  2005-02       Impact factor: 3.490

7.  Different requirements for σ Region 4 in BvgA activation of the Bordetella pertussis promoters P(fim3) and P(fhaB).

Authors:  Kimberly B Decker; Qing Chen; Meng-Lun Hsieh; Philip Boucher; Scott Stibitz; Deborah M Hinton
Journal:  J Mol Biol       Date:  2011-04-22       Impact factor: 5.469

8.  A new gene locus of Bordetella pertussis defines a novel family of prokaryotic transcriptional accessory proteins.

Authors:  T M Fuchs; H Deppisch; V Scarlato; R Gross
Journal:  J Bacteriol       Date:  1996-08       Impact factor: 3.490

9.  Synergistic binding of RNA polymerase and BvgA phosphate to the pertussis toxin promoter of Bordetella pertussis.

Authors:  P E Boucher; S Stibitz
Journal:  J Bacteriol       Date:  1995-11       Impact factor: 3.490

10.  BvgAS is sufficient for activation of the Bordetella pertussis ptx locus in Escherichia coli.

Authors:  M A Uhl; J F Miller
Journal:  J Bacteriol       Date:  1995-11       Impact factor: 3.490
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.