Literature DB >> 19389082

Autophagy and the immune response to TB.

J Harris1, J C Hope, E C Lavelle.   

Abstract

Autophagy is a homeostatic mechanism for the catabolism of cytosolic constituents, including organelles, in times of stress and nutrient deprivation. In addition, autophagy has been linked to innate and adaptive immune responses to numerous infectious microorganisms, including mycobacteria. This review explores the role of autophagy in the responses of antigen-presenting cells to mycobacteria, including links with phagosome maturation, inflammasome activation and antigen presentation. In addition, the modulation of autophagy by cytokines and pathogen-derived stimuli is discussed.

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Year:  2009        PMID： 19389082     DOI： 10.1111/j.1865-1682.2009.01069.x

Source DB:  PubMed          Journal:  Transbound Emerg Dis        ISSN： 1865-1674            Impact factor:   5.005


  19 in total

1.  Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction.

Authors:  Chong-Shan Shi; Kevin Shenderov; Ning-Na Huang; Juraj Kabat; Mones Abu-Asab; Katherine A Fitzgerald; Alan Sher; John H Kehrl
Journal:  Nat Immunol       Date:  2012-01-29       Impact factor: 25.606

Review 2.  Autophagy in the immune response to tuberculosis: clinical perspectives.

Authors:  C Ní Cheallaigh; J Keane; E C Lavelle; J C Hope; J Harris
Journal:  Clin Exp Immunol       Date:  2011-03-25       Impact factor: 4.330

3.  Depletion of L-arginine induces autophagy as a cytoprotective response to endoplasmic reticulum stress in human T lymphocytes.

Authors:  Rósula García-Navas; Markus Munder; Faustino Mollinedo
Journal:  Autophagy       Date:  2012-08-09       Impact factor: 16.016

4.  Atg7 Deficiency Intensifies Inflammasome Activation and Pyroptosis in Pseudomonas Sepsis.

Authors:  Qinqin Pu; Changpei Gan; Rongpeng Li; Yi Li; Shirui Tan; Xuefeng Li; Yuquan Wei; Lefu Lan; Xin Deng; Haihua Liang; Feng Ma; Min Wu
Journal:  J Immunol       Date:  2017-03-03       Impact factor: 5.422

Review 5.  How tumour necrosis factor blockers interfere with tuberculosis immunity.

Authors:  J Harris; J Keane
Journal:  Clin Exp Immunol       Date:  2010-05-18       Impact factor: 4.330

6.  The same well-characterized T cell epitope SIINFEKL expressed in the context of a cytoplasmic or secreted protein in BCG induces different CD8+ T cell responses.

Authors:  Paul D Hulseberg; Alla Zozulya; Hamlet H Chu; James A Triccas; Zsuzsanna Fabry; Matyas Sandor
Journal:  Immunol Lett       Date:  2009-12-11       Impact factor: 3.685

7.  Mycobacterium leprae upregulates IRGM expression in monocytes and monocyte-derived macrophages.

Authors:  Degang Yang; Jia Chen; Linglin Zhang; Zhanshan Cha; Song Han; Weiwei Shi; Ru Ding; Lan Ma; Hong Xiao; Chao Shi; Zhichun Jing; Ningjing Song
Journal:  Inflammation       Date:  2014-08       Impact factor: 4.092

8.  Autophagy gene polymorphism is associated with susceptibility to leprosy by affecting inflammatory cytokines.

Authors:  Degang Yang; Jia Chen; Chao Shi; Zhichun Jing; Ningjing Song
Journal:  Inflammation       Date:  2014-04       Impact factor: 4.092

Review 9.  Targeted pulmonary delivery of inducers of host macrophage autophagy as a potential host-directed chemotherapy of tuberculosis.

Authors:  Anuradha Gupta; Amit Misra; Vojo Deretic
Journal:  Adv Drug Deliv Rev       Date:  2016-01-29       Impact factor: 15.470

Review 10.  Mechanisms of NLRP3 Inflammasome Activation: Its Role in the Treatment of Alzheimer's Disease.

Authors:  Yidan Zhang; Yuan Zhao; Jian Zhang; Guofeng Yang
Journal:  Neurochem Res       Date:  2020-09-14       Impact factor: 3.996
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