Literature DB >> 19388709

Oleanane-type isomeric triterpenoids from Barringtonia racemosa.

P Mangala Gowri1, S V S Radhakrishnan, S Jeelani Basha, A V S Sarma, J Madhusudana Rao.   

Abstract

Two new isomeric acylated oleanane-type triterpenoids along with three known compounds were isolated from the MeOH extract of the dried fruits of Barringtonia racemosa. On the basis of spectroscopic methods, with special emphasis on 1D and 2D NMR techniques as well as chemical methods, the structures were characterized as racemosol A (1) [22alpha-acetoxy-3beta,15alpha,16alpha,21beta-tetrahydroxy-28-(2-methylbutyryl)olean-12-ene] and isoracemosol A (2) [21beta-acetoxy-3beta,15alpha,16alpha,28-tetrahydroxy-22alpha-(2-methylbutyryl)olean-12-ene]. The isolated compounds (1-5) were not active against HeLa and P388 D1 carcinoma cell lines.

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Year:  2009        PMID: 19388709     DOI: 10.1021/np8007396

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  6 in total

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5.  Treating type 2 diabetes mellitus with traditional chinese and Indian medicinal herbs.

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  6 in total

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