PURPOSE: To develop and demonstrate the feasibility of multisequence and multiplanar MRI for whole-body cancer detection. MATERIALS AND METHODS: Two fast Dixon-based sequences and a diffusion-weighted sequence were used on a commercially available 1.5 T scanner for whole-body cancer detection. The study enrolled 19 breast cancer patients with known metastases and in multistations acquired whole-body axial diffusion-weighted, coronal T2-weighted, axial/sagittal pre- and postcontrast T1-weighted, as well as triphasic abdomen images. Three radiologists subjectively scored Dixon images of each series for overall image quality and fat suppression uniformity on a 4-point scale (1 = poor, 2 = fair, 3 = good, and 4 = excellent). RESULTS: Eighteen of the 19 patients completed the whole-body MRI successfully. The mean acquisition time and overall patient table time were 46 +/- 3 and 69 +/- 5 minutes, respectively. The average radiologists' scores for overall image quality and fat suppression uniformity were both 3.4 +/- 0.5. The image quality was consistent between patients and all completed whole-body examinations were diagnostically adequate. CONCLUSION: Whole-body MRI offering essentially all the most optimal tumor-imaging sequences in a typical 1-hour time slot can potentially become an appealing "one-stop-shop" for whole-body cancer imaging.
PURPOSE: To develop and demonstrate the feasibility of multisequence and multiplanar MRI for whole-body cancer detection. MATERIALS AND METHODS: Two fast Dixon-based sequences and a diffusion-weighted sequence were used on a commercially available 1.5 T scanner for whole-body cancer detection. The study enrolled 19 breast cancerpatients with known metastases and in multistations acquired whole-body axial diffusion-weighted, coronal T2-weighted, axial/sagittal pre- and postcontrast T1-weighted, as well as triphasic abdomen images. Three radiologists subjectively scored Dixon images of each series for overall image quality and fat suppression uniformity on a 4-point scale (1 = poor, 2 = fair, 3 = good, and 4 = excellent). RESULTS: Eighteen of the 19 patients completed the whole-body MRI successfully. The mean acquisition time and overall patient table time were 46 +/- 3 and 69 +/- 5 minutes, respectively. The average radiologists' scores for overall image quality and fat suppression uniformity were both 3.4 +/- 0.5. The image quality was consistent between patients and all completed whole-body examinations were diagnostically adequate. CONCLUSION: Whole-body MRI offering essentially all the most optimal tumor-imaging sequences in a typical 1-hour time slot can potentially become an appealing "one-stop-shop" for whole-body cancer imaging.
Authors: V Schulz; I Torres-Espallardo; S Renisch; Z Hu; N Ojha; P Börnert; M Perkuhn; T Niendorf; W M Schäfer; H Brockmann; T Krohn; A Buhl; R W Günther; F M Mottaghy; G A Krombach Journal: Eur J Nucl Med Mol Imaging Date: 2010-10-05 Impact factor: 9.236
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Authors: Sharif Kershah; Sasan Partovi; Bryan J Traughber; Raymond F Muzic; Mark D Schluchter; James K O'Donnell; Peter Faulhaber Journal: Mol Imaging Biol Date: 2013-12 Impact factor: 3.488
Authors: James M Mullin; Katherine M Diguilio; Mary C Valenzano; Rachael Deis; Sunil Thomas; E Peter Zurbach; Shaheed Abdulhaqq; Luis J Montaner Journal: PLoS One Date: 2017-03-09 Impact factor: 3.240
Authors: Marcos Duarte Guimarães; Julia Noschang; Sara Reis Teixeira; Marcel Koenigkam Santos; Henrique Manoel Lederman; Vivian Tostes; Vikas Kundra; Alex Dias Oliveira; Bruno Hochhegger; Edson Marchiori Journal: Cancer Imaging Date: 2017-02-10 Impact factor: 3.909