| Literature DB >> 19388017 |
Pamela V Chang1, Xing Chen, Chris Smyrniotis, Alexander Xenakis, Tianshun Hu, Carolyn R Bertozzi, Peng Wu.
Abstract
Sialome sweet sialome: As sialic acids are involved in many host-pathogen recognition events and are markers of embryonic and malignant tissues, there is great interest in methods for the enrichment and identification of sialylated glycoproteins from complex tissues. Now N-(4-pentynoyl)mannosamine can be used to metabolically label sialylated glycoproteins in living animals, enabling future identification of new biomarkers.Entities:
Mesh:
Substances:
Year: 2009 PMID: 19388017 PMCID: PMC2868584 DOI: 10.1002/anie.200806319
Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN: 1433-7851 Impact factor: 15.336