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Literature DB >> 19387829

Acupuncture at both ST25 and ST37 improves the pain threshold of chronic visceral hypersensitivity rats.

Hui-Rong Liu¹, Xiao-Mei Wang, En-Hua Zhou, Yin Shi, Na Li, Ling-Song Yuan, Huan-Gan Wu.

Abstract

Previous studies demonstrated the efficacy of electro-acupuncture (EA) in relieving chronic visceral hypersensitivity (CVH) in IBS rats. However, ST25 which is a key acupoint for patients with IBS has not been reported in these experiments. Eight CVH rats were treated by EA at both ST25 and ST37 for 20 min, once daily for seven consecutive days, model rats (n = 8) and normal rats (n = 8) as controls. After the first EA treatment, the abdominal withdrawal reflex scores were investigated to evaluate the pain threshold. After seven EA treatments, the concentrations of 5-hydroxytryptamine (5-HT), 5-HT3 receptor (5-HT3R) and 5-HT4 receptor (5-HT4R) in colon tissue were assayed quantitatively by enzyme-linked immunosorbent assay. The results showed that EA improved the pain threshold of CVH rats, reduced the 5-HT concentration and increased the 5-HT4R concentration, but had no effect on the 5-HT3R concentration. Further studies are needed to optimize the choice of two-matching points for EA in the treatment of CVH rats.

Entities: Chemical Disease Gene Species

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Year: 2009 PMID： 19387829 DOI： 10.1007/s11064-009-9972-1

Source DB: PubMed Journal: Neurochem Res ISSN： 0364-3190 Impact factor: 3.996

21 in total

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2. Tegaserod, a 5-HT4 receptor partial agonist, decreases sensitivity to rectal distension in healthy subjects.

Authors: B Coffin; J-P Farmachidi; P Rueegg; A Bastie; D Bouhassira
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3. Acupuncture treatment for irritable bowel syndrome. A double-blind controlled study.

Authors: Z Fireman; A Segal; Y Kopelman; A Sternberg; R Carasso
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4. The 5-HT(3) receptor antagonist alosetron inhibits the colorectal distention induced depressor response and spinal c-fos expression in the anaesthetised rat.

Authors: C M Kozlowski; A Green; D Grundy; F M Boissonade; C Bountra
Journal: Gut Date: 2000-04 Impact factor: 23.059

5. The role of acupuncture in the treatment of irritable bowel syndrome: a pilot study.

Authors: J Chan; I Carr; J F Mayberry
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Review 6. 5-HT in the enteric nervous system: gut function and neuropharmacology.

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8. Repeated electro-acupuncture attenuates chronic visceral hypersensitivity and spinal cord NMDA receptor phosphorylation in a rat irritable bowel syndrome model.

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Review 9. The epidemiology of irritable bowel syndrome in North America: a systematic review.

Authors: Yuri A Saito; Philip Schoenfeld; G Richard Locke
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Review 10. Enterochromaffin cells and 5-HT signaling in the pathophysiology of disorders of gastrointestinal function.

Authors: Michael D Crowell; Michael A Shetzline; Peter L Moses; Gary M Mawe; Nicholas J Talley
Journal: Curr Opin Investig Drugs Date: 2004-01

26 in total

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3. Acupoint Specificity on Colorectal Hypersensitivity Alleviated by Acupuncture and the Correlation with the Brain-Gut Axis.

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4. Effect of electroacupuncture on P2X3 receptor regulation in the peripheral and central nervous systems of rats with visceral pain caused by irritable bowel syndrome.

Authors: Z J Weng; L Y Wu; C L Zhou; C Z Dou; Y Shi; H R Liu; H G Wu
Journal: Purinergic Signal Date: 2015-03-26 Impact factor: 3.765

5. Electroacupuncture in reduction of discomfort associated with barostat-induced rectal distension--a randomized controlled study.

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6. Electroacupuncture at ST-36 relieves visceral hypersensitivity and decreases 5-HT(3) receptor level in the colon in chronic visceral hypersensitivity rats.

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Journal: Int J Colorectal Dis Date: 2010-11-10 Impact factor: 2.571

10. Effects of Moxibustion Stimulation on the Intensity of Infrared Radiation of Tianshu (ST25) Acupoints in Rats with Ulcerative Colitis.

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Journal: Evid Based Complement Alternat Med Date: 2012-11-20 Impact factor: 2.629