BACKGROUND: Screening for malnutrition is recommended in hospitalized and planned surgical patients. The aim of this study was to analyze the feasibility and routine prognostic value of using the principal recommended nutritional screening and evaluation tools for cancer patients undergoing major surgery. METHODS: This study is a prospective, 3-month, multicenter observational trial recording weight loss, body mass index, albumin, transthyretin, and PG-SGA. The morbidity rate was assessed on the basis of major complications (MC), whether of an infectious (MIC) or noninfectious (MNIC) nature. RESULTS: Two hundred seventy-five patients were recruited at nine centers. The following percentages were recorded with respect to morbidity: 28.4% MC, 12.7% MIC, and 22.2% MNIC. Univariate analysis revealed a statistical association only between weight loss greater than 10% and MIC and hospital stay. A weight loss of 15% is required to demonstrate an association with either MC, MIC, or MNIC. Body mass index (BMI) was associated only with MNIC, PG-SGA with MC, and albumin <30 g/l was strongly associated with all types of morbidity (MC, MIC, MNIC). Multivariate analysis indicated that only albumin <30 g/l and an operating time of more than 4 h are significantly associated with morbidity. CONCLUSIONS: In this study, the best nutritional factor for detecting the risk of MC is albumin levels below 30 g/l. A weight loss greater than 15% is required to obtain a statistically significant correlation with the existence of MC.
BACKGROUND: Screening for malnutrition is recommended in hospitalized and planned surgical patients. The aim of this study was to analyze the feasibility and routine prognostic value of using the principal recommended nutritional screening and evaluation tools for cancerpatients undergoing major surgery. METHODS: This study is a prospective, 3-month, multicenter observational trial recording weight loss, body mass index, albumin, transthyretin, and PG-SGA. The morbidity rate was assessed on the basis of major complications (MC), whether of an infectious (MIC) or noninfectious (MNIC) nature. RESULTS: Two hundred seventy-five patients were recruited at nine centers. The following percentages were recorded with respect to morbidity: 28.4% MC, 12.7% MIC, and 22.2% MNIC. Univariate analysis revealed a statistical association only between weight loss greater than 10% and MIC and hospital stay. A weight loss of 15% is required to demonstrate an association with either MC, MIC, or MNIC. Body mass index (BMI) was associated only with MNIC, PG-SGA with MC, and albumin <30 g/l was strongly associated with all types of morbidity (MC, MIC, MNIC). Multivariate analysis indicated that only albumin <30 g/l and an operating time of more than 4 h are significantly associated with morbidity. CONCLUSIONS: In this study, the best nutritional factor for detecting the risk of MC is albumin levels below 30 g/l. A weight loss greater than 15% is required to obtain a statistically significant correlation with the existence of MC.
Authors: F Bozzetti; C Gavazzi; R Miceli; N Rossi; L Mariani; L Cozzaglio; G Bonfanti; S Piacenza Journal: JPEN J Parenter Enteral Nutr Date: 2000 Jan-Feb Impact factor: 4.016
Authors: G P Buzby; L S Knox; L O Crosby; J M Eisenberg; C M Haakenson; G E McNeal; C P Page; O L Peterson; G F Reinhardt; W O Williford Journal: Am J Clin Nutr Date: 1988-02 Impact factor: 7.045
Authors: W D Dewys; C Begg; P T Lavin; P R Band; J M Bennett; J R Bertino; M H Cohen; H O Douglass; P F Engstrom; E Z Ezdinli; J Horton; G J Johnson; C G Moertel; M M Oken; C Perlia; C Rosenbaum; M N Silverstein; R T Skeel; R W Sponzo; D C Tormey Journal: Am J Med Date: 1980-10 Impact factor: 4.965
Authors: Malcolm K Robinson; Elaine B Trujillo; Kris M Mogensen; Jan Rounds; Katherine McManus; Danny O Jacobs Journal: JPEN J Parenter Enteral Nutr Date: 2003 Nov-Dec Impact factor: 4.016
Authors: Benjamin H L Tan; Torill Fladvad; Theodore P Braun; Antonio Vigano; Florian Strasser; D A Christopher Deans; Richard J E Skipworth; Tora S Solheim; Sambasivarao Damaraju; James A Ross; Stein Kaasa; Daniel L Marks; Vickie E Baracos; Frank Skorpen; Kenneth C H Fearon Journal: EMBO Mol Med Date: 2012-04-04 Impact factor: 12.137
Authors: Paweł Kabata; Tomasz Jastrzębski; Michał Kąkol; Karolina Król; Maciej Bobowicz; Anna Kosowska; Janusz Jaśkiewicz Journal: Support Care Cancer Date: 2014-08-06 Impact factor: 3.603