Literature DB >> 19386862

Intravenous thrombolysis for ischaemic stroke: short delays and high community-based treatment rates after organisational changes in a previously inexperienced centre.

A Tveiten1, A Mygland, U Ljøstad, L Thomassen.   

Abstract

AIM: To evaluate hospital delays in thrombolytic treatment before and after organisational changes and community-based treatment rates in a previously inexperienced centre.
METHODS: The delays before and after organisational changes made in 2006 were compared using a prospective treatment database. In a 6-month period in 2007, a community-based search was performed for all hospitalisations for ischaemic stroke. The number of patients admitted within the 0-3 h time window and the proportion treated with tissue plasminogen activator were analysed.
RESULTS: The number of treatments increased fourfold from 2005 to 2007 with a significant reduction in mean door-to-needle time from 60 min to 38 min (p = 0.002). In the community-based series, 14/137 patients (10%) hospitalised with ischaemic stroke and 13/32 patients (41%) admitted in the 0-3 h window were treated.
CONCLUSIONS: An inexperienced stroke centre can rapidly implement the necessary logistics to deliver thrombolysis to a large proportion of patients with acute stroke with short hospital delays. Important factors are probably prenotification of a team and the initiation of thrombolytic treatment in the emergency room.

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Year:  2009        PMID: 19386862     DOI: 10.1136/emj.2008.063610

Source DB:  PubMed          Journal:  Emerg Med J        ISSN: 1472-0205            Impact factor:   2.740


  10 in total

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3.  Why don't more patients receive intravenous rt-PA for acute stroke?

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4.  The "golden hour" and acute brain ischemia: presenting features and lytic therapy in >30,000 patients arriving within 60 minutes of stroke onset.

Authors:  Jeffrey L Saver; Eric E Smith; Gregg C Fonarow; Mathew J Reeves; Xin Zhao; Daiwai M Olson; Lee H Schwamm
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Review 5.  Reducing prehospital delay in acute stroke.

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6.  An analysis of outcomes of emergency physician/department-based thrombolysis for stroke.

Authors:  A P Volans
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7.  Stroke code improves intravenous thrombolysis administration in acute ischemic stroke.

Authors:  Chih-Hao Chen; Sung-Chun Tang; Li-Kai Tsai; Ming-Ju Hsieh; Shin-Joe Yeh; Kuang-Yu Huang; Jiann-Shing Jeng
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8.  Impact of emergency room meetings on improvement of door-to-needle times in acute ischemic stroke patients: A single center's experience.

Authors:  Bilgehan Atilgan Acar
Journal:  North Clin Istanb       Date:  2018-09-10

9.  Factors delaying intravenous thrombolytic therapy in acute ischaemic stroke: a systematic review of the literature.

Authors:  Angelos Sharobeam; Brett Jones; Dianne Walton-Sonda; Christian J Lueck
Journal:  J Neurol       Date:  2020-03-21       Impact factor: 4.849

10.  Estimating Costs of Implementing Stroke Systems of Care and Data-Driven Improvements in the Paul Coverdell National Acute Stroke Program.

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Journal:  Prev Chronic Dis       Date:  2019-10-03       Impact factor: 2.830

  10 in total

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