| Literature DB >> 19386512 |
Abstract
CD4+ T(H)17 cells display a featured role in barrier immunity. This effector population of T cells is important for clearance of microorganisms but can also promote autoimmunity at barrier sites. Recent work has indicated that these effector cells share a pathway with CD4+ regulatory T cells (T(R) cells) that also have a critical function in barrier protection and immune regulation. The development and function of T(H)17 cells, and their relationship with T(R) cells are discussed.Entities:
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Year: 2009 PMID: 19386512 PMCID: PMC2692766 DOI: 10.1016/j.smim.2009.03.001
Source DB: PubMed Journal: Semin Immunol ISSN: 1044-5323 Impact factor: 11.130