Literature DB >> 19385962

Treating miscarriages: a randomised study of cost-effectiveness in medical or surgical choice.

M Niinimäki1, P Karinen, A-L Hartikainen, A Pouta.   

Abstract

OBJECTIVE: The aim was to carry out a cost effectiveness analysis (CEA) of medical and surgical treatment of miscarriage using quantitative and qualitative indicators.
DESIGN: A prospective study where the data of the clinical course of the treatment and the patients; experiences (pain and satisfaction) were collected from a previous randomised study.
SETTING: Department of Obstetrics and Gynecology, Oulu University Hospital, Oulu, Finland. POPULATION: Ninety-eight eligible women with a diagnosed miscarriage.
METHODS: The incremental cost-effectiveness ratio (ICER) was calculated by using institutional prices (provider's aspect) of the medical care and the number of patients who experienced pain, dissatisfaction or unsuccessful treatment while treated for the miscarriage. MAIN OUTCOME MEASURES: Primary (uncomplicated treatment) and secondary (complications and other unplanned events) costs of the treatments.
RESULTS: Primary costs of the surgical treatment were higher, but the more frequent unplanned events and complications in the medical group brought the costs to the same level. In the medical group, based on the ICER, 12 patients more experienced pain, 7 patients more were dissatisfied with the treatment and 5 patients more had unsuccessful treatment compared with surgically treated patients. In theory, these negative outcomes could have been avoided by investing euro1688 more in the surgical treatment.
CONCLUSIONS: Medical treatment of miscarriage was not more cost-effective, when the adverse events were considered. As neither of these two methods was economically superior, the treatment choice should be made on an individual basis by respecting the patient's choice.

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Year:  2009        PMID: 19385962     DOI: 10.1111/j.1471-0528.2009.02161.x

Source DB:  PubMed          Journal:  BJOG        ISSN: 1470-0328            Impact factor:   6.531


  10 in total

Review 1.  Medical treatments for incomplete miscarriage (less than 24 weeks).

Authors:  James P Neilson; Gillian Ml Gyte; Martha Hickey; Juan C Vazquez; Lixia Dou
Journal:  Cochrane Database Syst Rev       Date:  2010-01-20

Review 2.  Medical treatments for incomplete miscarriage.

Authors:  Caron Kim; Sharmani Barnard; James P Neilson; Martha Hickey; Juan C Vazquez; Lixia Dou
Journal:  Cochrane Database Syst Rev       Date:  2017-01-31

3.  Medical treatment for early fetal death (less than 24 weeks).

Authors:  Marike Lemmers; Marianne Ac Verschoor; Bobae Veronica Kim; Martha Hickey; Juan C Vazquez; Ben Willem J Mol; James P Neilson
Journal:  Cochrane Database Syst Rev       Date:  2019-06-17

4.  Practice variation in the management of first trimester miscarriage in the Netherlands: a nationwide survey.

Authors:  Marianne A C Verschoor; Marike Lemmers; Malu Z Wekker; Judith A F Huirne; Mariëtte Goddijn; Ben Willem J Mol; Willem M Ankum
Journal:  Obstet Gynecol Int       Date:  2014-11-04

5.  Trends of Patients' Preferences in the Management of First and Early Second Trimester Pregnancy Loss Towards the Choice of Medical or Surgical Termination of Pregnancy in a Tertiary Care Center in Oman.

Authors:  Tamima Al-Dughaishi; Mussab Mubarak Hamed Al-Jabri; Amjad Hamed Al-Haddabi; Vaidyanathan Gowri
Journal:  J Reprod Infertil       Date:  2019 Jan-Mar

Review 6.  Economic evaluation of medical versus surgical strategies for first trimester therapeutic abortion: A systematic review.

Authors:  Saeed Husseini Barghazan; Mohamad Hadian; Aziz Rezapour; Setare Nassiri
Journal:  J Educ Health Promot       Date:  2022-06-30

7.  Surgical versus expectant management in women with an incomplete evacuation of the uterus after treatment with misoprostol for miscarriage: the MisoREST trial.

Authors:  Marianne A C Verschoor; Marike Lemmers; Patrick M Bossuyt; Giuseppe C M Graziosi; Petra J Hajenius; Dave J Hendriks; Marcel A H van Hooff; Hannah S van Meurs; Brent C Opmeer; Maurits W van Tulder; Liesanne Bouwma; Ruby Catshoek; Peggy Geomini; Ellen R Klinkert; Josje Langenveld; Theodoor E Nieboer; J Marinus van der Ploeg; Celine M Radder; Taeke Spinder; Lucy F van der Voet; Ben Willem J Mol; Judith A F Huirne; Willem M Ankum
Journal:  BMC Pregnancy Childbirth       Date:  2013-05-02       Impact factor: 3.007

8.  Methods for managing miscarriage: a network meta-analysis.

Authors:  Jay Ghosh; Argyro Papadopoulou; Adam J Devall; Hannah C Jeffery; Leanne E Beeson; Vivian Do; Malcolm J Price; Aurelio Tobias; Özge Tunçalp; Antonella Lavelanet; Ahmet Metin Gülmezoglu; Arri Coomarasamy; Ioannis D Gallos
Journal:  Cochrane Database Syst Rev       Date:  2021-06-01

9.  Medical Abortion Provided by Nurse-Midwives or Physicians in a High Resource Setting: A Cost-Effectiveness Analysis.

Authors:  Susanne Sjöström; Helena Kopp Kallner; Emilia Simeonova; Andreas Madestam; Kristina Gemzell-Danielsson
Journal:  PLoS One       Date:  2016-06-30       Impact factor: 3.240

Review 10.  Reporting and Analysis of Trial-Based Cost-Effectiveness Evaluations in Obstetrics and Gynaecology.

Authors:  Mohamed El Alili; Johanna M van Dongen; Judith A F Huirne; Maurits W van Tulder; Judith E Bosmans
Journal:  Pharmacoeconomics       Date:  2017-10       Impact factor: 4.981

  10 in total

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