OBJECTIVE: To investigate the chemical constituents of the aerial roots of Ficus microcarpa. METHOD: The solvent extraction and silica gel and Sephadex LH-20 column chromatography were used to isolate and purify the constituents. The chemical structures were elucidated by physicochemical properties and the analysis of spectroscopic data. RESULT: Eight compounds were obtained and identified as (2S, 3S, 4R) -2-[(2'R) -2' - hydroxypentracosanoylamino]- heptadecane -1, 3, 4-triol (1), 12, 20 (30) -ursa-dien-3alpha-ol (2), epifriedelanol (3), alpha-amyrin acetate (4), beta-sitosterol (5), beta-daucosterol (6), hexacosanoic acid (7), heneicosanoic acid (8), respectively. CONCLUSION: Compound 1 was a new compound and named as microcarpaceramide A. Compound 2 was isolated from the aerial roots of F. microcarpa for the first time.
OBJECTIVE: To investigate the chemical constituents of the aerial roots of Ficus microcarpa. METHOD: The solvent extraction and silica gel and Sephadex LH-20 column chromatography were used to isolate and purify the constituents. The chemical structures were elucidated by physicochemical properties and the analysis of spectroscopic data. RESULT: Eight compounds were obtained and identified as (2S, 3S, 4R) -2-[(2'R) -2' - hydroxypentracosanoylamino]- heptadecane -1, 3, 4-triol (1), 12, 20 (30) -ursa-dien-3alpha-ol (2), epifriedelanol (3), alpha-amyrin acetate (4), beta-sitosterol (5), beta-daucosterol (6), hexacosanoic acid (7), heneicosanoic acid (8), respectively. CONCLUSION: Compound 1 was a new compound and named as microcarpaceramide A. Compound 2 was isolated from the aerial roots of F. microcarpa for the first time.
Authors: Kamran Ashraf; Mohd Rafiul Haque; Mohd Amir; Niyaz Ahmad; Wasim Ahmad; Sadia Sultan; Syed Adnan Ali Shah; Ahmed Mahmoud Alafeefy; Mohd Mujeeb; Muhammad Fikriey Bin Shafie Journal: J Pharm Bioallied Sci Date: 2020-12-25