Literature DB >> 19384162

Assessment of cadaveric organ viability during pulsatile perfusion using infrared imaging.

Alexander M Gorbach1, David B Leeser, Hengliang Wang, Douglas K Tadaki, Carlos Fernandez, David Destephano, Douglas Hale, Allan D Kirk, Fred A Gage, Eric A Elster.   

Abstract

Assessment of pulsatile perfusion (PP) is limited to measurements of flow (V) and resistance (R). We investigated infrared (IR) imaging during PP as a means for precise organ assessment. IR was used to monitor 10 porcine kidneys during 18 hr of PP in an uncontrolled Donation after Cardiac Death model. An IR camera (Lockheed Martin) was focused on the anterior surfaces of the kidneys. The degree of temperature homogeneity was compared with standard measurements of V and R. IR thermal images correlated with V and R (R=0.92, P<0.001). IR detected an increase in homogeneity during PP by comparing standard deviation differences before and after PP (P=0.002), which was not evident by standard measurements of V and R. Finally, IR assessment allowed for measurement of dynamic changes in perfusion.

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Year:  2009        PMID: 19384162      PMCID: PMC2751614          DOI: 10.1097/TP.0b013e31819e3e02

Source DB:  PubMed          Journal:  Transplantation        ISSN: 0041-1337            Impact factor:   4.939


  7 in total

1.  Machine perfusion and viability assessment of non-heart-beating donor kidneys-a single-centre result.

Authors:  S Balupuri; D Mantle; M Mohamed; B Shenton; M Gok; N Soomro; D M Manas; J Kirby; D Talbot
Journal:  Transplant Proc       Date:  2001 Feb-Mar       Impact factor: 1.066

2.  Laparoscopic infrared imaging.

Authors:  J A Cadeddu; S V Jackman; P G Schulam
Journal:  J Endourol       Date:  2001-02       Impact factor: 2.942

3.  Objective, real-time, intraoperative assessment of renal perfusion using infrared imaging.

Authors:  Alexander Gorbach; Donna Simonton; Douglas A Hale; S John Swanson; Allan D Kirk
Journal:  Am J Transplant       Date:  2003-08       Impact factor: 8.086

4.  Comparison of static versus pulsatile preservation of matched-paired kidneys.

Authors:  F Gage; M Ali; M R Alijani; A O Aquino; D Y Barhyte; C O Callender; J O Colonna; C B Currier; C Fernandez-Bueno; J Jonsson; A E Kowalski; J L Romolo; T M Sasaki; T R Shaver; S J Swanson; J A Light
Journal:  Transplant Proc       Date:  1997-12       Impact factor: 1.066

5.  Improved immediate function of renal allografts with Belzer perfusate.

Authors:  M L Henry; B G Sommer; R M Ferguson
Journal:  Transplantation       Date:  1988-01       Impact factor: 4.939

6.  Effectiveness of machine perfusion preservation as a viability determination method for kidneys procured from non-heart-beating donors.

Authors:  N Matsuno; E Sakurai; I Tamaki; K Furuhashi; A Saito; S Zhang; K Kozaki; A Shimada; K Miyamoto; M Kozaki
Journal:  Transplant Proc       Date:  1994-08       Impact factor: 1.066

7.  The influence of pulsatile preservation on renal transplantation in the 1990s.

Authors:  M M Polyak; B O Arrington; W T Stubenbord; J Boykin; T Brown; M A Jean-Jacques; J Estevez; S Kapur; M Kinkhabwala
Journal:  Transplantation       Date:  2000-01-27       Impact factor: 4.939

  7 in total

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