Literature DB >> 19383598

Epidemiology and clinical presentation of gonorrhoea in England and Wales: findings from the Gonococcal Resistance to Antimicrobials Surveillance Programme 2001-2006.

V Delpech1, I M C Martin, G Hughes, T Nichols, L James, C A Ison.   

Abstract

OBJECTIVE: To analyse the enhanced data for gonorrhoea cases in England and Wales collected by the Gonococcal Resistance to Antimicrobials Surveillance Programme (GRASP) to better inform health policy and targeted interventions.
METHODS: GRASP data obtained annually from sentinel genitourinary medicine (GUM) clinics between June to August during 2001-6 were analysed.
RESULTS: A total of 12 282 cases of gonorrhoea were reported during the study period, with a decline over time primarily in heterosexual patients of black ethnicity. 73% of women, 47% of heterosexual men and 22% of men who have sex with men (MSM) were aged under 25. Most infected women reported a single sexual partner in the previous 3 months, whereas most heterosexual men and MSM reported two or more partners. A history of gonorrhoea was reported by 42% of MSM, 30% of heterosexual men and 20% of women. Excluding HIV, women were more likely than men to have a concurrent STI at diagnosis, most commonly chlamydia (50% vs 27% p<0.0005). Rectal gonococcal infections were reported in 35% and HIV co-infection in 31% of MSM. Compared to HIV negative MSM, those co-infected with HIV were older (median 35 years vs 28 years) and were more likely to attend a London site (70% vs 52%, p<0.0005); have a concurrent sexually transmitted infection (STI) (28% vs 20%, p = 0.002); have a history of gonorrhoea (66% vs 36%, p<0.0005) and have more sexual partners (average 6.8 vs 4.3).
CONCLUSION: Gonorrhoea is concentrated within specific groups who are at high risk of repeat infections and concurrent STIs including HIV. Targeted interventions of proved effectiveness are urgently required.

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Year:  2009        PMID: 19383598     DOI: 10.1136/sti.2008.034843

Source DB:  PubMed          Journal:  Sex Transm Infect        ISSN: 1368-4973            Impact factor:   3.519


  6 in total

Review 1.  Periurethral abscess complicating gonococcal urethritis: case report and literature review.

Authors:  A Kenfak-Foguena; Y Zarkik; M Wisard; V Praz; K E A Darling; K Jaton-Ogay; P Jichlinski; M Cavassini
Journal:  Infection       Date:  2010-09-03       Impact factor: 3.553

2.  Azithromycin resistance and its mechanism in Neisseria gonorrhoeae strains in Hyogo, Japan.

Authors:  Katsumi Shigemura; Kayo Osawa; Makiko Miura; Kazushi Tanaka; Soichi Arakawa; Toshiro Shirakawa; Masato Fujisawa
Journal:  Antimicrob Agents Chemother       Date:  2015-02-23       Impact factor: 5.191

3.  The epidemiology of gonorrhoea in London: a Bayesian spatial modelling approach.

Authors:  O Le Polain De Waroux; R J Harris; G Hughes; P D Crook
Journal:  Epidemiol Infect       Date:  2013-04-08       Impact factor: 4.434

4.  Prevention of Ophthalmia Neonatorum Caused by Neisseria gonorrhoeae Using a Fatty Acid-Based Formulation.

Authors:  Colin P Churchward; Raid G Alany; Ruth S Kirk; Anthony J Walker; Lori A S Snyder
Journal:  MBio       Date:  2017-07-25       Impact factor: 7.867

5.  Gonorrhoea diagnoses in a network of STI clinics in Spain during the period 2006-2010: differences by sex and transmission route.

Authors:  Asuncion Diaz; Cesar Garriga; Jose Antonio Varela; Elisa Fernández; Isabel Sanz; Josep Boronat; Fuensanta Gual; Concepcion Colomo; Josefina López de Munain; Valentin Esteban; Maria Luisa Junquera; Blanca Martínez; Isabel Pueyo; Justo Suárez; Maria Jesus Barberá; Maider Arando; Jose Manuel Ureña; Mercedes Diez
Journal:  BMC Public Health       Date:  2013-11-25       Impact factor: 3.295

6.  The Growing Threat of Gonococcal Blindness.

Authors:  Victoria Dolange; Colin P Churchward; Myron Christodoulides; Lori A S Snyder
Journal:  Antibiotics (Basel)       Date:  2018-07-12
  6 in total

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