| Literature DB >> 19383026 |
S Goriely1, R Cavoy, M Goldman.
Abstract
Cytokines produced by antigen-presenting cells govern the fate of helper T-cell responses. Herein, we review the impact of interleukin (IL)-23 and IL-27 on the outcome of T-helper (Th) 17 cell responses and discuss their impact in the pathogenesis of T-cell-mediated inflammatory disorders of autoimmune or allergic origin. We then discuss how type I interferons might influence the course of autoimmune diseases by tipping the balance between IL-12 family members.Entities:
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Year: 2009 PMID: 19383026 DOI: 10.1111/j.1398-9995.2009.02039.x
Source DB: PubMed Journal: Allergy ISSN: 0105-4538 Impact factor: 13.146