| Literature DB >> 19382779 |
Kenneth C Parker1, Ronan J Walsh, Mohammad Salajegheh, Anthony A Amato, Bryan Krastins, David A Sarracino, Steven A Greenberg.
Abstract
We characterized the human muscle proteome by studying muscle biopsy specimens through four different workflows, using 1 or 2D peptide separation, SDS gels, or differential solubilization. By performing MS/MS analyses of 178 4-h LC separations derived from 31 patients, we identified more than 2000 proteins, and determined how 370 very abundant proteins behave upon differential solubilization. The resulting semiquantitative database should serve as a resource for muscle biochemistry.Entities:
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Year: 2009 PMID: 19382779 DOI: 10.1021/pr800873q
Source DB: PubMed Journal: J Proteome Res ISSN: 1535-3893 Impact factor: 4.466