Palladium nanoparticles, generated in situ from the reaction of palladium(II) chloride, have been demonstrated to be an efficient catalyst for C-N bond formation. A variety of aliphatic and aromatic amines have been allylated by substituted and unsubstituted allyl acetates in high yields by using palladium nanoparticles in the presence of a base without any ligand. The allylations are highly regio- and stereoselective.
Palladiumnanoparticles, generated in situ from the reaction of n class="Chemical">palladium(II) chloride, have been demonstrated to be an efficient catalyst for C-N bond formation. A variety of aliphatic and aromatic amines have been allylated by substituted and unsubstituted allyl acetates in high yields by using palladium nanoparticles in the presence of a base without any ligand. The allylations are highly regio- and stereoselective.
Authors: Helen L Parker; Elizabeth L Rylott; Andrew J Hunt; Jennifer R Dodson; Andrew F Taylor; Neil C Bruce; James H Clark Journal: PLoS One Date: 2014-01-29 Impact factor: 3.240