Literature DB >> 1938234

Deoxyribonuclease activity in lymphocytes of patients with chronic renal failure treated conservatively.

R Adamiec1, Z Szewczyk, J Prochera, J Szopa.   

Abstract

The activity of nucleases and concentrations of highly important metal ions in T and B lymphocytes were examined. The source of lymphocyte was the blood of patients with chronic renal failure and activity of enzyme as well as ion concentrations were compared to the control group. Concomitant with the increase in enzyme activity was an increase of metal ion concentrations assayed in both T and B lymphocytes isolated from patients with renal disease. The data suggest that the enhancement of nuclease activity is a result of increased enzyme polypeptide synthesis and its stimulation by metal ions. Utilization of the nuclease test for monitoring uraemic toxicity is considered.

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Year:  1991        PMID： 1938234     DOI： 10.1007/bf02549610

Source DB:  PubMed          Journal:  Int Urol Nephrol        ISSN： 0301-1623            Impact factor:   2.370


  8 in total

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Authors:  A Górski
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Authors:  T E Miller; E Stewart
Journal:  Clin Exp Immunol       Date:  1980-07       Impact factor: 4.330

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Journal:  Lab Invest       Date:  1980-06       Impact factor: 5.662

8.  Impaired cellular immune responses in chronic renal failure: evidence for a T cell defect.

Authors:  P Kurz; H Köhler; S Meuer; T Hütteroth; K H Meyer zum Büschenfelde
Journal:  Kidney Int       Date:  1986-06       Impact factor: 10.612
  8 in total
  1 in total

1.  Deoxyribonuclease activity in T and B lymphocytes of haemodialysed patients with uraemia.

Authors:  R Adamiec; Z Szewczyk; J Szopa
Journal:  Int Urol Nephrol       Date:  1992       Impact factor: 2.370
  1 in total

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