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Literature DB >> 19382115

Evidence for pseudoknot formation of class I preQ1 riboswitch aptamers.

Ulrike Rieder¹, Kathrin Lang, Christoph Kreutz, Norbert Polacek, Ronald Micura.

Abstract

All in a knot. The smallest riboswitch forms a pseudoknot in solution. This is demonstrated for preQ(1) class I aptamers by mutational analysis in combination with (1)H NMR-based structure probing. How pseudoknot formation mediates the mRNA response through its expression platform is now open for investigation.

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Year: 2009 PMID： 19382115 DOI： 10.1002/cbic.200900155

Source DB: PubMed Journal: Chembiochem ISSN： 1439-4227 Impact factor: 3.164

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Cited

25 in total

1. Folding of a transcriptionally acting preQ1 riboswitch.

Authors: Ulrike Rieder; Christoph Kreutz; Ronald Micura
Journal: Proc Natl Acad Sci U S A Date: 2010-06-01 Impact factor: 11.205

Review 2. Riboswitch structure in the ligand-free state.

Authors: Joseph A Liberman; Joseph E Wedekind
Journal: Wiley Interdiscip Rev RNA Date: 2011-09-28 Impact factor: 9.957

3. Mg(2+) shifts ligand-mediated folding of a riboswitch from induced-fit to conformational selection.

Authors: Krishna C Suddala; Jiarui Wang; Qian Hou; Nils G Walter
Journal: J Am Chem Soc Date: 2015-10-29 Impact factor: 15.419

4. Tuning a riboswitch response through structural extension of a pseudoknot.

Authors: Marie F Soulière; Roger B Altman; Veronika Schwarz; Andrea Haller; Scott C Blanchard; Ronald Micura
Journal: Proc Natl Acad Sci U S A Date: 2013-08-12 Impact factor: 11.205

5. Minimizing base loss and internal fragmentation in collisionally activated dissociation of multiply deprotonated RNA.

Authors: Monika Taucher; Ulrike Rieder; Kathrin Breuker
Journal: J Am Soc Mass Spectrom Date: 2009-10-21 Impact factor: 3.109

6. A conserved RNA pseudoknot in a putative molecular switch domain of the 3'-untranslated region of coronaviruses is only marginally stable.

Authors: Suzanne N Stammler; Song Cao; Shi-Jie Chen; David P Giedroc
Journal: RNA Date: 2011-07-28 Impact factor: 4.942

Evidence for pseudoknot formation of class I preQ1 riboswitch aptamers.

1. Folding of a transcriptionally acting preQ1 riboswitch.

Review 2. Riboswitch structure in the ligand-free state.

3. Mg(2+) shifts ligand-mediated folding of a riboswitch from induced-fit to conformational selection.

4. Tuning a riboswitch response through structural extension of a pseudoknot.

5. Minimizing base loss and internal fragmentation in collisionally activated dissociation of multiply deprotonated RNA.

6. A conserved RNA pseudoknot in a putative molecular switch domain of the 3'-untranslated region of coronaviruses is only marginally stable.

Review 7. Structure and function of preQ₁ riboswitches.

8. Photochemical control of RNA structure by disrupting π-stacking.

9. 5-Fluoro pyrimidines: labels to probe DNA and RNA secondary structures by 1D 19F NMR spectroscopy.

Review 10. Amino acid recognition and gene regulation by riboswitches.

Review 2. Riboswitch structure in the ligand-free state.

Review 7. Structure and function of preQ1 riboswitches.

Review 10. Amino acid recognition and gene regulation by riboswitches.

Review 7. Structure and function of preQ₁ riboswitches.