Literature DB >> 19381383

Design of liposome-based pH sensitive nanoSPIN probes: nano-sized particles with incorporated nitroxides.

Yakov Y Woldman1, Sergey V Semenov, Andrey A Bobko, Igor A Kirilyuk, Julya F Polienko, Maxim A Voinov, Elena G Bagryanskaya, Valery V Khramtsov.   

Abstract

Liposome-based nanoSized Particles with Incorporated Nitroxides, or nanoSPINs, were designed for EPR applications as pH probes in biological systems. Phospholipid membrane of the liposomes with incorporated gramicidin A showed selective permeability to a small analyte, H(+), while protecting entrapped sensing nitroxide from biological reductants. An application of the pH-sensitive nanoSPIN in an ischemia model in rat heart homogenate allows for monitoring ischemia-induced acidosis while protecting encapsulated nitroxide against bioreduction.

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Year:  2009        PMID： 19381383      PMCID： PMC2897711          DOI： 10.1039/b818184e

Source DB:  PubMed          Journal:  Analyst        ISSN： 0003-2654            Impact factor:   4.616


  30 in total

Review 1.  Optochemical nanosensor PEBBLEs: photonic explorers for bioanalysis with biologically localized embedding.

Authors:  Sarah M Buck; Yong-Eun Lee Koo; Ed Park; Hao Xu; Martin A Philbert; Murphy A Brasuel; Raoul Kopelman
Journal:  Curr Opin Chem Biol       Date:  2004-10       Impact factor: 8.822

2.  Small-volume extrusion apparatus for preparation of large, unilamellar vesicles.

Authors:  R C MacDonald; R I MacDonald; B P Menco; K Takeshita; N K Subbarao; L R Hu
Journal:  Biochim Biophys Acta       Date:  1991-01-30

3.  Quantitation of nitric oxide using 2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl 3-oxide (PTIO).

Authors:  T Akaike; H Maeda
Journal:  Methods Enzymol       Date:  1996       Impact factor: 1.600

4.  Semipermeable aqueous microcapsules. I. Preparation and properties.

Authors:  T M Chang; F C MacIntosh; S G Mason
Journal:  Can J Physiol Pharmacol       Date:  1966-01       Impact factor: 2.273

5.  In vivo oximetry using a nitroxide-liposome system.

Authors:  J F Glockner; H C Chan; H M Swartz
Journal:  Magn Reson Med       Date:  1991-07       Impact factor: 4.668

6.  In vivo measurement of oxygen concentration using sonochemically synthesized microspheres.

Authors:  K J Liu; M W Grinstaff; J Jiang; K S Suslick; H M Swartz; W Wang
Journal:  Biophys J       Date:  1994-08       Impact factor: 4.033

7.  Trapping of nitric oxide by nitronyl nitroxides: an electron spin resonance investigation.

Authors:  J Joseph; B Kalyanaraman; J S Hyde
Journal:  Biochem Biophys Res Commun       Date:  1993-04-30       Impact factor: 3.575

8.  Spin trapping of nitric oxide by nitronylnitroxides: measurement of the activity of no synthase from rat cerebellum.

Authors:  V V Khramtsov; I A Grigor'ev; I A Kiriljuk; D I Utepbergenov
Journal:  Biochem Biophys Res Commun       Date:  1994-07-15       Impact factor: 3.575

9.  Antagonistic action of imidazolineoxyl N-oxides against endothelium-derived relaxing factor/.NO through a radical reaction.

Authors:  T Akaike; M Yoshida; Y Miyamoto; K Sato; M Kohno; K Sasamoto; K Miyazaki; S Ueda; H Maeda
Journal:  Biochemistry       Date:  1993-01-26       Impact factor: 3.162

10.  The diffusion of L(+)-ascorbic acid across DPPC vesicle membranes.

Authors:  H Sapper; K D Röth; W Lohmann
Journal:  J Microencapsul       Date:  1985 Jan-Mar       Impact factor: 3.142
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  11 in total

1.  Electron paramagnetic resonance monitoring of ischemia-induced myocardial oxygen depletion and acidosis in isolated rat hearts using soluble paramagnetic probes.

Authors:  Denis A Komarov; Ilirian Dhimitruka; Igor A Kirilyuk; Dmitrii G Trofimiov; Igor A Grigor'ev; Jay L Zweier; Valery V Khramtsov
Journal:  Magn Reson Med       Date:  2011-12-12       Impact factor: 4.668

2.  Direct chemiluminescence detection of nitric oxide in aqueous solutions using the natural nitric oxide target soluble guanylyl cyclase.

Authors:  Yakov Y Woldman; Jian Sun; Jay L Zweier; Valery V Khramtsov
Journal:  Free Radic Biol Med       Date:  2009-09-12       Impact factor: 7.376

3.  Ionizable Nitroxides for Studying Local Electrostatic Properties of Lipid Bilayers and Protein Systems by EPR.

Authors:  Maxim A Voinov; Alex I Smirnov
Journal:  Methods Enzymol       Date:  2015-09-09       Impact factor: 1.600

4.  In vivo monitoring of pH, redox status, and glutathione using L-band EPR for assessment of therapeutic effectiveness in solid tumors.

Authors:  Andrey A Bobko; Timothy D Eubank; Jeffrey L Voorhees; Olga V Efimova; Igor A Kirilyuk; Sergey Petryakov; Dmitrii G Trofimiov; Clay B Marsh; Jay L Zweier; Igor A Grigor'ev; Alexandre Samouilov; Valery V Khramtsov
Journal:  Magn Reson Med       Date:  2011-11-23       Impact factor: 4.668

Review 5.  Exchange Phenomena in the Electron Paramagnetic Resonance Spectra of the Nitroxyl and Trityl Radicals: Multifunctional Spectroscopy and Imaging of Local Chemical Microenvironment.

Authors:  Valery V Khramtsov; Andrey A Bobko; Mark Tseytlin; Benoit Driesschaert
Journal:  Anal Chem       Date:  2017-04-10       Impact factor: 6.986

Review 6.  In Vivo Molecular Electron Paramagnetic Resonance-Based Spectroscopy and Imaging of Tumor Microenvironment and Redox Using Functional Paramagnetic Probes.

Authors:  Valery V Khramtsov
Journal:  Antioxid Redox Signal       Date:  2017-12-20       Impact factor: 8.401

7.  Variable radio frequency proton-electron double-resonance imaging: application to pH mapping of aqueous samples.

Authors:  Olga V Efimova; Ziqi Sun; Sergey Petryakov; Eric Kesselring; George L Caia; David Johnson; Jay L Zweier; Valery V Khramtsov; Alexandre Samouilov
Journal:  J Magn Reson       Date:  2011-01-15       Impact factor: 2.229

8.  Variable Field Proton-Electron Double-Resonance Imaging: Application to pH mapping of aqueous samples.

Authors:  Valery V Khramtsov; George L Caia; Keerthi Shet; Eric Kesselring; Sergey Petryakov; Jay L Zweier; Alexandre Samouilov
Journal:  J Magn Reson       Date:  2009-11-26       Impact factor: 2.229

9.  Discriminative EPR detection of NO and HNO by encapsulated nitronyl nitroxides.

Authors:  Andrey A Bobko; Alexander Ivanov; Valery V Khramtsov
Journal:  Free Radic Res       Date:  2012-11-28

10.  In vivo proton-electron double-resonance imaging of extracellular tumor pH using an advanced nitroxide probe.

Authors:  Alexandre Samouilov; Olga V Efimova; Andrey A Bobko; Ziqi Sun; Sergey Petryakov; Timothy D Eubank; Dmitrii G Trofimov; Igor A Kirilyuk; Igor A Grigor'ev; Wataru Takahashi; Jay L Zweier; Valery V Khramtsov
Journal:  Anal Chem       Date:  2014-01-06       Impact factor: 6.986
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