Literature DB >> 19380591

Simultaneous determination of voriconazole and posaconazole concentrations in human plasma by high-performance liquid chromatography.

Kathrin Kahle1, Peter Langmann, Diana Schirmer, Ulrike Lenker, Daniela Keller, Annegret Helle, Hartwig Klinker, Werner J Heinz.   

Abstract

A simple, sensitive, and selective high-performance liquid chromatographic method for the simultaneous determination of voriconazole and posaconazole concentrations in human plasma was developed and validated. Quantitative recovery following liquid-liquid extraction with diethyl ether was achieved. Linearity ranged from 0.10 to 20.0 microg/ml for voriconazole and from 0.05 to 10.0 microg/ml for posaconazole. The intra- and interday coefficients of variation were less than 8.5%, and the lower limits of quantitation were <0.05 microg/ml.

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Year:  2009        PMID： 19380591      PMCID： PMC2704663          DOI： 10.1128/AAC.00213-09

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  19 in total

1.  Development and validation of a high-performance liquid chromatography assay for voriconazole.

Authors:  Gennethel J Pennick; Martin Clark; Deanna A Sutton; Michael G Rinaldi
Journal:  Antimicrob Agents Chemother       Date:  2003-07       Impact factor: 5.191

Review 2.  Rare and emerging opportunistic fungal pathogens: concern for resistance beyond Candida albicans and Aspergillus fumigatus.

Authors:  M A Pfaller; D J Diekema
Journal:  J Clin Microbiol       Date:  2004-10       Impact factor: 5.948

Review 3.  Cytochromes P450 in fungi.

Authors:  H Vanden Bossche; L Koymans
Journal:  Mycoses       Date:  1998       Impact factor: 4.377

4.  A rapid HPLC assay for voriconazole in human plasma.

Authors:  R Gage; D A Stopher
Journal:  J Pharm Biomed Anal       Date:  1998-09       Impact factor: 3.935

5.  Determination of a new antifungal agent, voriconazole, by multidimensional high-performance liquid chromatography with direct plasma injection onto a size-exclusion column.

Authors:  D A Stopher; R Gage
Journal:  J Chromatogr B Biomed Sci Appl       Date:  1997-04-11

6.  Comparison of high-performance liquid chromatographic and microbiological methods for determination of voriconazole levels in plasma.

Authors:  S Perea; G J Pennick; A Modak; A W Fothergill; D A Sutton; D J Sheehan; M G Rinaldi
Journal:  Antimicrob Agents Chemother       Date:  2000-05       Impact factor: 5.191

Review 7.  Voriconazole: a new triazole antifungal agent.

Authors:  Leonard B Johnson; Carol A Kauffman
Journal:  Clin Infect Dis       Date:  2003-02-10       Impact factor: 9.079

8.  Use of high-performance liquid chromatographic and microbiological analyses for evaluating the presence or absence of active metabolites of the antifungal posaconazole in human plasma.

Authors:  Hong Kim; Pramila Kumari; Mark Laughlin; Mary Jane Hilbert; Stephen R Indelicato; Josephine Lim; Chin-Chung Lin; Amin A Nomeir
Journal:  J Chromatogr A       Date:  2003-02-14       Impact factor: 4.759

9.  Determination of voriconazole in human plasma and saliva using high-performance liquid chromatography with fluorescence detection.

Authors:  Claudia Michael; Jens Teichert; Rainer Preiss
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2008-03-10       Impact factor: 3.205

10.  Effect of posaconazole on cytochrome P450 enzymes: a randomized, open-label, two-way crossover study.

Authors:  D Wexler; R Courtney; W Richards; C Banfield; J Lim; M Laughlin
Journal:  Eur J Pharm Sci       Date:  2004-04       Impact factor: 4.384
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  8 in total

1.  Ultra-performance liquid chromatography mass spectrometry and sensitive bioassay methods for quantification of posaconazole plasma concentrations after oral dosing.

Authors:  Bertrand Rochat; Andres Pascual; Benoît Pesse; Frédéric Lamoth; Dominique Sanglard; Laurent A Decosterd; Jacques Bille; Oscar Marchetti
Journal:  Antimicrob Agents Chemother       Date:  2010-10-04       Impact factor: 5.191

2.  Relevance of timing for determination of posaconazole plasma concentrations.

Authors:  Werner J Heinz; Janina Zirkel; Anna Kuhn; Diana Schirmer; Ulrike Lenker; Daniela Keller; Hartwig Klinker
Journal:  Antimicrob Agents Chemother       Date:  2011-04-18       Impact factor: 5.191

3.  Detection of posaconazole by surface-assisted laser desorption/ionization mass spectrometry with dispersive liquid-liquid microextraction.

Authors:  Sheng-Yu Lin; Pin-Shiuan Chen; Sarah Y Chang
Journal:  J Am Soc Mass Spectrom       Date:  2015-01-06       Impact factor: 3.109

4.  Determination of voriconazole serum concentration by bioassay, a valid method for therapeutic drug monitoring for clinical laboratories.

Authors:  Emilio Cendejas-Bueno; Manuel Cuenca-Estrella; Alicia Gomez-Lopez
Journal:  Antimicrob Agents Chemother       Date:  2013-05-06       Impact factor: 5.191

Review 5.  Posaconazole exposure-response relationship: evaluating the utility of therapeutic drug monitoring.

Authors:  Michael J Dolton; John E Ray; Deborah Marriott; Andrew J McLachlan
Journal:  Antimicrob Agents Chemother       Date:  2012-03-05       Impact factor: 5.191

6.  Efficacy, safety and feasibility of antifungal prophylaxis with posaconazole tablet in paediatric patients after haematopoietic stem cell transplantation.

Authors:  Michaela Döring; Karin Melanie Cabanillas Stanchi; Manon Queudeville; Judith Feucht; Franziska Blaeschke; Patrick Schlegel; Tobias Feuchtinger; Peter Lang; Ingo Müller; Rupert Handgretinger; Werner J Heinz
Journal:  J Cancer Res Clin Oncol       Date:  2017-03-03       Impact factor: 4.553

7.  Analysis of imidazoles and triazoles in biological samples after MicroExtraction by packed sorbent.

Authors:  Cristina Campestre; Marcello Locatelli; Paolo Guglielmi; Elisa De Luca; Giuseppe Bellagamba; Sergio Menta; Gokhan Zengin; Christian Celia; Luisa Di Marzio; Simone Carradori
Journal:  J Enzyme Inhib Med Chem       Date:  2017-12       Impact factor: 5.051

Review 8.  Assessment of greenness for the determination of voriconazole in reported analytical methods.

Authors:  Hemanth Kumar Chanduluru; Abimanyu Sugumaran
Journal:  RSC Adv       Date:  2022-02-28       Impact factor: 3.361
  8 in total

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